Title: "Induced oxidative stress in anticancer activity."
Speaker: Kastauv Sahoo, Ph.D. candidate, Dept. of Pharmaceutical Sciences, OU College of Pharmacy
Time: Noon-1 pm
Reactive oxygen species (ROS) serves as an essential messenger in many biological processes in normal cells. However, in cancer cells, the redox status is perturbed, and many cancers are characterized by higher levels of oxidative stress and up-regulated anti-oxidant mechanisms. This unique feature of cancer cells could be exploited for a therapeutic advantage in the treatment of cancer, implying modulation of redox homeostasis as an anticancer strategy. Recent literature on this issue and our own experience in developing a novel anticancer molecular CLEFMA will be discussed.