SEM and rehabilitation

 

Peek, M. Kristen PhD. Structural Equation Modeling and Rehabilitation Research.

American Journal of Physical Medicine & Rehabilitation. 79(3):301-309, May/June 2000.

 

Structural equation modeling (SEM) has been used extensively in the social sciences in the recent past to model human behavior. SEM has been less used by other disciplines, including rehabilitation medicine. This article begins by providing an introduction to structural equation modeling through the discussion of the definition and basic concepts behind SEM using a conceptual model relevant to rehabilitation medicine that describes the pathway from health to disability (the Enabling-Disabling model). The next focus is on several potential pitfalls of which the researcher needs to be aware when using SEM. After this discussion, a hypothetical example is presented using structural equation modeling to evaluate the Enabling-Disabling model. The article concludes with a review of the advantages and disadvantages of using SEM for clinical and social science research. Throughout the article, references are provided for a more detailed examination of SEM.   (32 ref)

 

Comment: Peek advocates using the SEM with the disablement model and suggests that it "has successfully been used" (p. 302).  Quotes Lawrence and Jette (1996, disentangling) on the need for "clinical trials" that illuminate causal relationships among impairment, disability, and the entire disablement process, including "risk factors" that may change over time.

 

      The article includes Figure 2 (p.304), which illustrates a structural model in which a quality of life measure rests at the end of a series of exogenous and endogenous variables.

 

      ???Lawrence and Jette (1996) cast doubt on the existence of a direct relationship between pathology and disability, but I believe that they did not use SEM.  They indicate that functional limitations or abilities are most directly related to disability.

 

 Peek has published examples of use of SEM models (search for his name in this page)

 

 

 
 
Bartlett, D.J., & Palisano, R.J. (2002). Physical therapists' perceptions of factors influencing the acquisition of motor abilities of children with cerebral palsy: Implications for clinical reasoning. Physical Therapy, 82 (3), 237-248.

        http://www.ptjournal.org/PTJournal/March2002/v82n3p237.cfm

 

 

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Mulligan, S. (1998). Application of structural equation modeling in occupational therapy research. American Journal of Occupational Therapy, 52, 829-34.

 

Occupational Therapy Department, School of Health and Human Sciences, University of New Hampshire, Hewitt Hall, 4 Library Way, Durham, New Hampshire 03824-3563.

 

Structural equation modeling (SEM) is a relatively new research method for analyzing multivariate data. This article provides an introduction and overview of what SEM is and identifies some potential uses of this technique for occupational therapy researchers. The application of SEM in the areas of test construction and treatment effectiveness is highlighted, some cautionary measures related to this technique are presented, and resources that provide more detailed and advanced reading on the subject are included.

 

Comment:  Mulligan has published a study in which she used CFA for a dyspraxia instrument (see later in this page)

 

 

Hepburn, D. A., Deary, I. J., MacLeod, K. M., & Frier, B. M. (1994). Structural equation modelling of symptoms, awareness, and fear of hypoglycaemia and personality in patients with insulin-treated diabetes. Diabetes Care, 17, 1273-1280.

 

 

 

Gold, A. E, Frier, B. M., MacLeod, K. M., & Deary, I. J. (1997). A structural equation model for predictors of severe hypoglycaemia in patients with insulin-dependent diabetes mellitus. Diabetic Medicine, 14, 309-315.

 

 

Hawkins WE, Duncan T. Structural equation analysis of an exercise/sleep health practices model on quality of life of elderly persons. Percept Mot Skills 1991;72(3 Pt 1):831-6.

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Bartlett, D.J., & Palisano, R.J. (2000). A multivariate model for determinants of motor change for children with cerebral palsy. Physical Therapy, 80,598-614. 

 

e-mail: d.bartlett@uwo.ca. Assistant Professor, School of Physical Therapy, Faculty of Health Sciences, University of Western Ontario, 1588 Elborn College, London, Ontario, Canada N6G 1H1

 

Abstract

  The purpose of this article is to describe the development of a theory- and data-based model of determinants of motor change for children with cerebral palsy. The dimensions of human functioning proposed by the World Health Organization, general systems theory, theories of human ecology, and a philosophical approach incorporating family-centered care provide the conceptual framework for the model. The model focuses on relationships among child characteristics (eg, primary and secondary impairments, personality), family ecology (eg, dynamics of family function), and health care services (eg, availability, access, intervention options). Clarification of the complex multivariate and interactive relationships among the multiple child and family determinants, using statistical methods such as structural equation modeling, is necessary before determining how physical therapy intervention can optimize motor outcomes of children with cerebral palsy. We propose that the development and testing of multivariate models is also useful in physical therapy research and in the management of complex chronic conditions other than cerebral palsy. Testing of similar models could provide physical therapists with support for: (1) prognostic discussions with clients and their families, (2) establishment of realistic and attainable goals, and (3) interventions to enhance outcomes for individual clients with a variety of prognostic attributes.   (109 ref)

 

DMT's Summary:  The article's first part summarizes SEM, and is less useful in doing so than similar treatments in the rehabilitation literature (Peek, ; Mulligan,   ).  The article's second part describes in detail how the authors constructed theory-driven structural and measurement models.  Their five-factor structural model is an example of a "sequential longitudinal" model (MacCallum & Austin, 2000, p. 205).  They also discuss their plans for building a measurement model.

 

The authors discuss the advantages of SEM approaches to understanding disablement, particularly  in children with CP.  They advocate SEM as a way of deciding whether impairments like co-contraction are best understood as primary problems or secondary adaptations.  Primary and secondary impairments can be distinguished in a sequential model by the timing of their appearance as factors; primary factors appear around the time of diagnosis, while secondary impairments appear later.  Building and comparing of competing structural models could shed light on such the identity of particular impairments.

 

 

 

Available online: http://www.ptjournal.org/PTJournal/June2000/v80n6p598.cfm

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Sousa KH.  Chen F.

Assistant Professor, College of Nursing, Arizona State University, Tempe, AZ.

 

Conference Abstract

 

Health-Related quality of life theory and structural equation modeling... 34th Annual Communicating Nursing Research Conference/15th Annual WIN Assembly, "Health Care Challenges Beyond 2001: Mapping the Journey for Research and Practice," held April 19-21, 2001 in Seattle, Washington.

Source

  Communicating Nursing Research,  34(9):290, 2001 Spring.

 

 

Karen Sousa

http://nursing.asu.edu/facultystaff/sousak.htm

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Comment:  Studies of cardiac care may be especially interesting in terms of the types of data challenges they present.  Examples:

 

 

1.

Riegel BJ.  Dracup KA.  Glaser D.

Institution

  School of Nursing, San Diego State University, Sharp HealthCare, CA, USA.

Title

  A longitudinal causal model of cardiac invalidism following myocardial infarction.

Source

  Nursing Research.  47(5):285-92, 1998 Sep-Oct.

 

Abstract

  BACKGROUND: Invalidism has been discussed in the cardiovascular literature for decades. Researchers have studied health perceptions, emotional distress, and dependency in patients after acute myocardial infarction in an attempt to understand the phenomenon. However, no theory of the manner in which these variables interact has been proposed. OBJECTIVES: Using previous research, a model of invalidism was specified in which individuals' perceptions that their health is poor lead to emotional distress and increased dependency. As health perceptions improve over time, emotional distress and dependency decrease. METHOD: Survey data were collected from 111 men and women 1 and 4 months after a first myocardial infarction and were tested using structural equation modeling. RESULTS: The model was rejected using a confirmatory approach (chi2(89) = 141.40; p= .00034). The fit indices, however, suggested an adequate fit of the model to the data (CFI = .96; NNFI = .94). CONCLUSION: The conclusion is that the model is reasonable and serves as a starting point for a theory-based empirical exploration of the invalidism process.

 

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2.

Riegel B.  Dracup K.

Institution

  Sharp Memorial Hosp, San Diego, CA.

Title

  Social support and cardiac invalidism following acute myocardial infarction.

Source

  Heart & Lung: Journal of Critical Care,  21(3):298, 1992 May.

 

Abstract

  At least 25% of acute myocardial infarction (AMI) patients experience long-term adjustment problems such as cardiac invalidism defined as a complex of low self-esteem (SE), emotional distress (ED), poor health perceptions (HP), and interpersonal dependency (ID). A theoretical model was tested in which social support was hypothesized to influence cardiac invalidism following AMI. A survey design was used to collect data from 111 first AMI patients 1 and 4 months following hospital discharge. The data fit the model well when tested with structural equation modeling with data obtained at 1 month (comparative fit index (CFI)=.997, p=.42) and with change scores (CFI=1.0, p=.92). At 1 month SS predicted ID (-.87) and health outlook (.26). HP predicted ED (-.26) and SE (.33). ED predicted SS desired (.39). SE predicted ED (-.57). Using change scores, SS predicted ED (.53) and HP (-.41). SE predicted ED (-.25). HP predicted anger (.20). ID predicted SS received (-.39). Thus, SS was !

a significant predictor of cardiac invalidism following AMI. The recovery process was dynamic at 1 month but less so at 4 months. Interventions designed to prevent cardiac invalidism should begin during or immediately after hospital discharge and should focus on augmenting and refining social support.

 

 

3.

 

Fontana AF.  Kerns RD.  Rosenberg RL.  Colonese KL.

Support, stress, and recovery from coronary heart disease: a longitudinal causal model.

Health Psychology.  8(2):175-93, 1989.

 

Measures of support, stress, distress, and cardiac symptoms were obtained from a cohort of 73 male cardiac patients at hospitalization and at 3, 6, and 12 months thereafter. Sets of general and alternative hypotheses regarding the direction of causality among these variables were drawn from the literature on cardiac rehabilitation, stress, and support. Structural equation modeling was used to evaluate the stability and duration of these hypotheses over three time-lags. The results showed strong support for the general hypotheses and minimal support for the alternative hypotheses. Support ameliorated the subsequent experience of stress and distress and had opposing effects to these variables on cardiac symptoms. Support was more influential in the first half of the year than it was in the second half, however, whereas stress was predominant causally in the second half. Implications of this pattern for clinical intervention are drawn and directions for further research are proposed.

 

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Resnick B.  Daly MP. (1998).  Predictors of functional ability in geriatric rehabilitation patients.  Rehabilitation Nursing.  23(1):21-9, 1998 Jan-Feb.

 

University of Maryland, Baltimore, USA.

 

This study explored the impact that motivation, cognitive status, depression, age, and physical status have on the functional ability of older adults in a rehabilitation program. The study was based on a hypothesized model and was conducted with 200 patients on a geriatric rehabilitation unit. Structural equation modeling was done to test the hypothesized model. The average age of participants was 78 years, and the majority were female, Caucasian, unmarried, and had been admitted for rehabilitation after an orthopedic event. The data fit the hypothesized model; however, only five paths were significant. Mental status was a significant predictor of function on admission and a direct and indirect predictor of function at discharge, and diagnosis and age directly predicted function at discharge.

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Duncan TE.  Stoolmiller M. (1993).  Modeling social and psychological determinants of exercise behaviors via structural equation systems. Research Quarterly for Exercise & Sport.  64(1):1-16, 1993 Mar.

 

Oregon Social Learning Center, Eugene.

 

Recent advances in structural modeling techniques allow for the testing of complex models representing social and behavioral processes. However, most reported applications in sport and physical activity have been limited to simple models involving variables measured at a single point in time. Therefore, the purpose of this article is to demonstrate the use of both cross-sectional and longitudinal latent variable modeling techniques by examining the relationships among efficacy cognitions, social support, and the exercise behaviors of sedentary adults. Results revealed a good fit for the re-specified model, suggesting the existence of a lagged feedback mechanism in which exercise behaviors influenced residual change in social support. In turn, efficacy cognitions appeared to serve a mediational function in the synchronous relationship between social support and exercise behavior. Findings are discussed in terms of the utility of structural equation modeling techniques for und!

erstanding the complex social and cognitive processes involved in exercise behavior.

 

 

 

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SEM and falling

 

Preliminary searches of the literature in Medline do not reveal sources.  The area ought to be ripe for investigation.

 

Lawrence RH.  Tennstedt SL.  Kasten LE.  Shih J.  Howland J.  Jette AM. (1998). Intensity and correlates of fear of falling and hurting oneself in the next year: baseline findings from a Roybal Center fear of falling intervention.  Journal of Aging & Health.  10(3):267-86, 1998 Aug.

 

New England Research Institutes, USA.

 

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Lawrence RH.  Jette AM. (1996).  Disentangling the disablement process.  Journals of Gerontology Series B-Psychological Sciences & Social Sciences,  51B(4):S173-82, 1996 Jul.  (43 ref)

 

ReneeL%NERI@MCImail.com.  New England Research Institutes, 9 Galen Street, Watertown, MA 02172. Internet:

 

 

 

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Lichtenstein MJ.  Dhanda R.  Cornell JE.  Escalante A.  Hazuda HP.  (2000). Modeling impairment: using the disablement process as a framework to evaluate determinants of hip and knee flexion.  Aging (Milano).  12(3):208-20, 2000 Jun.

 

  Division of Geriatrics and Gerontology, University of Texas Health Science Center at San Antonio 78284, USA. lichtenstei@uthscsa.edu

 

Elders often present to health care providers with multiple inter-related conditions that determine an individual's ability to function. The disablement process provides a generalized sociomedical framework for investigating the complex pathways from chronic disease to disability. At each stage of the main pathway, associations may exist among primary physical factors and modifying variables that ultimately have downstream effects on the progression toward disability. The purpose of the present analysis is to examine the inter-relationships between a cohesive set of variables primarily at the level of impairment that may affect hip and knee flexion range of motion (ROM). The San Antonio Longitudinal Study of Aging enrolled 833 community dwelling Mexican (MA) and European American (EA) elders aged 64-78 years between 1992 and 1996. Of these, 647 had complete data from both a home-based and performance-based battery of assessments for these analyses. Concerning impairments, hip ROM was measured using an inclinometer, and knee ROM using a goniometer. Pain location and intensity were assessed using the McGill Pain Questionnaire. Peripheral vascular disease was assessed using doppler brachial and ankle systolic blood pressures. Ankle and knee reflexes, and vibratory sensation were assessed by a standardized neurological examination. As to diseases, diabetes was assessed using a combination of blood glucose levels and self-report, and arthritis by self-report. Concerning modifying variables, height and weight were directly measured and used to calculate BMI. Activity level was assessed with the Minnesota Leisure Time Questionnaire. Analgesic use was assessed by direct observation of medications taken within the past two weeks. We used structural equation modeling to test associations between the variables that were specified a priori. These analyses demonstrate the central role of BMI as a determinant of hip and knee flexion ROM. For an increase in level of BMI, the coefficients [SEM] for changes in levels of hip and knee ROM were -0.38 [0.05] and -0.26 [0.05], respectively. A higher BMI resulted in lower hip and knee ROM. BMI was also directly associated with prevalent diabetes (0.10 [0.05]) and arthritis (0.17 [0.05]). However, after adjustment for BMI, diabetes and arthritis did not have direct independent associations with either hip or knee ROM. BMI was also indirectly associated with knee, but not hip, ROM through paths including lower-leg pain, pain intensity, and neurosensory impairments. Diabetes had an indirect association with hip, but not knee ROM, through a path including peripheral vascular disease. In conclusion, BMI is a primary direct determinant of hip and knee ROM. The paths by which diabetes and arthritis lead to physical disability may be mediated, in part, at the level of impairment by BMI's association with joint range of motion. Interventions designed to decrease the impact of diabetes and arthritis on disability should track changes in BMI and joint ROM to measure the paths that account for the intervention's success. The observed associations suggest that interventions targeted to decrease BMI itself may lead to improved function in part through improved joint ROM.