Answer and Discussion of Quiz Set: U-001
3. Extracranial pituitary adenoma is most frequently found in which of the following locations?
A. Sphenpid sinus.
B. Clivus.
C. Pharynx and/or nasopharynx.
D. Cavernous sinus.
Answer and Discussion: The answer is (A). According to one study (Hori et al., 1999), about 64% of these tumors arises from the sphenoid sinus and another 4% that involves both the sphenoid sinus and pharynx. The clivus may be the least common site.
Further Reading:
Hori A, Schmidt D, Kuebber S. Immunohistochemical survey of migration of human anterior pituitary cells in developmental, pathological, and clinical aspects: a review. Microsc Res Tech. 1999 Jul 1;46(1):59-68.