Answer and Discussion of Quiz Set: W-001

1.    Which of the following tumors is least likely to metastasize to bone?

A.  Leiomyosarcoma

B.  Renal cell carcinoma

C.  Adenocarcinoma arising in the lung

D.  Invasive ductal carcinoma arising in the breast

E.  Prostate carcinoma

Answer and Discussion: The answer is (A). In general, sarcoma has much lower tendency to metastasize to bone in comparison to carcinoma. The most common metastatic carcinoma to the bone are those from the kidney, prostate, lung, breast, and kidney (all listed here).