Case of the Month Published in Brain Pathology

International Society of Neuropathology

Listed by site and type with diagnosis.

Sorted by chronological order  Sorted without diagnosis

Site Code

B-  Brain & head

S-   Spinal cord & vertebral column

P-  Pituitary & sellar area

M- Muscle

N-  Peripheral nerve biopsy

O-  Others, unclassified, & mixed

Type Code

C-      Congenital malformation

D-      Neurodegenerative disease

F-      Forensic, intoxication, iatrogenic, & medication related

G-      Genetic and/or metabolic

I-       Infection, inflammation, & demyelination

NH-   Neoplasm, hematological, histiocytic, & dendritic

NM-  Metastasis

NN-   Neoplasm, neuroepithelial/neuroectodermal

NO-   Neoplasm, others

T-      Tumor and tumor like lesions

U-      Unclassified or mixed

V-      Vascular (including vasculitis)

 

Site

Type

Number

Clinical Information

Diagnosis

B

C

BP-2015-08-314

A 59 year-old man with disseminated lung carcinoma and abnormal posterior fossa.

Dandy-Walker-Malformation. Mature midline posterior fossa teratoma. Metastatic lung adenocarcinoma to the right cerebellar hemisphere.

B

C

BP-2008-04-163

Neonate with occipital scalp defect.

Primary acalvaria, polymicrogyria, and partial destruction of brain stem and cerebellum.

B

D

BP-2014-04-282

A 63 year-old woman with dyspnoea, dysphagia and weakness.

Multiple system atrophy.

B

D

BP-2012-06-236

A 71 year-old woman with atypical Parkinson’s disease.

Parkinson disease and hypoxic-ischemic encephalopathy.

B

D

BP-2011-03-216

An 88 year-old woman with Parkinsonism.

Post encephalitic Parkinsonism.

B

D

BP-2007-04-137

A 12-year-old girl with seizures and dementia.

Lafora body disease.

B

D

BP-2000-07-052

A 70 year-old male with rigidity, decreased ocular movements, and dementia.

Progressive supranuclear palsy.

B

D

BP-1999-09-042

A 24-year-old female with progressive lower extremity dystonia, dysarthia, dysphagia and mental impairment.

Hallervorden-Spatz disease (neurodegeneration with axonal spheroids and iron depositions).

B

D

BP-1997-08-017

A 13 year-old girl with progressive movement disorder.

Huntington’s disease, juvenile onset.

B

F

BP-2018-03-376

A 56 year-old woman with esophageal carcinoma, pancytopenia and visual loss.

Leukoencephalopathy, consistent with fludarabine neurotoxicity.

B

F

BP-2016-12-345

A 3 year-old boy with progressive hemiparesis and thalamic tumor.

Gossypiboma (Textiloma) and residual pilocytic astrocytoma WHO grade I.

B

F

BP-2008-04-162

A 50 year-old man with Burkitt lymphoma.

Methotrexate-induced leukoencephalopathy

B

F

BP-2005-06-111

A 62-year-old man with chronic pyothorax.

Pyothorax-associated lymphoma.

B

F

BP-2000-08-053

Two patients with putamen and white matter necrosis and hemorrhage.

Methanol intoxication.

B

G

BP-2014-12-297

A 13 year-old female with ADHD, cognitive delay and seizures.

Niemann-Pick Disease, Type C.

B

G

BP-2009-04-185

A 22 year-old woman with status epilepticus.

Progressive myoclonus epilepsy Lafora-type (LD, OMIM# 254780), confirmed also by genetic testing, revealing a homozygous missense mutation (c.205C>G, P69A) in the EPM2B (NHLRC1) gene.

B

G

BP-2007-11-151

A 53 year-old male with rapid cognitive decline.

Kufs' Disease (Adult Neuronal Ceroid Lipofuscinosis).

B

G

BP-2007-04-137

A 12-year-old girl with seizures and dementia.

Lafora body disease.

B

G

BP-2006-01-118

A 70 year-old man with extrapyramidal symptoms, dementia and hemosiderosis.

Hereditary cerulopasmin deficiency with hemosiderosis.

B

G

BP-2005-10-115

A 48 year-old male with sudden onset of right sided weakness.

Posterior leukoencephalopathy; thrombotic microangiopathy related to thrombotic thrombocytopenic purpura (TTP).

B

I

BP-2019-09-412

A 70 year-old man presented with worsening cognition, speech impairment, ataxia, and dysphagia, periodic episodes of brachial dystonia, choreiform movements, and facial grimacing.

Limbic encephalitis due to LGI1 antibodies.

B

I

BP-2019-09-411

A 64 year-old man with visual disturbance and hippocampal swelling.

Anti-Leucine Rich Glioma Inactivated 1 (LGI1) - Autoimmune-mediated Limbic Encephalitis.

B

I

BP-2019-04-401

A 77 year-old woman with tinnitus and mantle cell lymphoma.

Atypical gliosis with reactive changes, no evidence of mantle cell lymphoma. The overall features are suggestive of progressive multifocal leukoencephalopathy (PML). In situ hybridization was positive for JC virus.

B

I

BP-2019-03-400

A 37 year-old woman with cramps.

Cerebral Schistosomiasis Caused by Schistosoma Mansoni.

B

I

BP-2019-03-399

A 55 year-old man with fever and headache.

Neuroschistosomiasis, cerebellar acute schistosomal encephalopathy infected by Schistosoma japonicum.

B

I

BP-2018-11-392

A 42 year-old man with asthma, headache and nausea.

Acute Hemorrhagic Leukoencephalitis (AHL) - Weston-Hurst's disease.

B

I

BP-2017-12-370

A 55 year-old man with headache and deep seated cerebral mass.

Cerebral schistosomiasis.

B

I

BP-2017-12-369

A 27 year-old woman with hemiparesis and cystic intracranial lesions.

Multiple intracranial tuberculomas.

B

I

BP-2017-04-354

A 32 year-old male with headache, visual loss and callosal lesion.

Neurotuberculosis with parenchymatous acute arteritis and cortical infarction.

B

I

BP-2016-03-327

A 63 year-old woman with apathy and drowsiness.

Rheumatoid meningitis.

B

I

BP-2015-12-321

A 52 year-old man with somnolence, irritability and memory disturbace.

Cerebral Whipple's disease.

B

I

BP-2015-08-313

A 59 year-old man with confusion, personality change and periventricular lesions on MRI.

Polymorphous post - transplant lymphoproliferative disorder, EBV positive (PTLD).

B

I

BP-2015-03-303

A 67 year-old man with long history of MS and cerebellar lesion.

Progressive multifocal leukoencephalopathy (PML) with superimposed immune reconstitution inflammatory syndrome (IRIS).

Quiescent multiple sclerosis plaques in multiple areas.

B

I

BP-2014-07-288

A 20 year-old man with haedache, photophobia and reduced GCS.

Tuberculous meningitis.

B

I

BP-2014-07-287

A 70 year-old male farmer with intermittent confusion.

Necrotizing granulomatous encephalitis with Mycobacterium caprae.

B

I

BP-2014-06-286

A 20 year-old man with spastic tratrapareisis and hearing loss.

Idiopathic hypertrophic pachymeningitis.

B

I

BP-2014-01-273

A 58 year old HIV positive Caucasian male presented with weight and appetite loss over 2 to 3 months.

Progressive Multifocal Leukoencephalopathy (PML) associated with Immune Reconstitution Inflammatory Syndrome (IRIS).

B

I

BP-2013-12-275

A 54 year-old man with eye pain and visual loss.

IgG4-related meningeal disease, previously classified as idiopathic hypertrophic pachymeningitis (IHP).

B

I

BP-2013-11-271

A 72 year-old woman with SLE and recent onset headache and ataxia.

Progressive multifocal leukoencephalopathy (PML) in Systemic Lupus Erythematosus (SLE).

B

I

BP-2013-07-262

A 39 year-old male with fever and headaches.

Toxoplasmosis of the hypothalamus, AIDS patient.

B

I

BP-2012-12-248

A 30 year-old male with headache, hearing impairment and blackout.

Schwannoma with exuberant inflammatory infiltrate and intratumoral edema that may have caused the increase of mass effect and sudden clinical deterioration.

B

I

BP-2012-11-247

A 63 year-old woman with polycythaemia, vertigo, ataxia and weakness.

Rosai Dorfman disease and multiple sclerosis.

B

I

BP-2012-11-246

A year-old man with sudden onset leg numbness.

Neurosarcodosiss.

B

I

BP-2012-05-235

A 49 year-old man with fever, altered mental state and enhancing brain lesions on MRI.

Disseminated Nocardiosis.

B

I

BP-2012-03-231

A 47 year-old male with HIV infection and hemiplegia.

Invasive aspergillosis of the CNS with secondary hemorrhagic infarcts and subarachnoid hemorrhage in a patient with AIDS.

B

I

BP-2011-10-223

A 2 year-old with anuria, diarrhoea and decreasing conscious level.

Pneumocephalus due to Clostridium septicum in association with hemolytic uremic syndrome.

B

I

BP-2009-12-200

A 45-year-old male with left-sided hemi-hypesthesia.

Tumefactive multiple sclerosis.

B

I

BP-2009-11-198

A 76 year-old woman with paraplegia.

 

CNS spread of untreated acute myeloid leukemia associated with acute demyelination.

B

I

BP-2009-08-193

A 35 year-old HIV-positive woman with brain lesion.

Acute adenovirus encephalitis.

B

I

BP-2009-08-192

A 7 year-old boy with acute encephalopathy.

Influenza associated acute necrotizing encephalopathy (ANE).

B

I

BP-2009-01-179

A 31 year-old man with Balint’s syndrome.

Subacute sclerosing encephalitis (SSPE) and craniopharyngioma.

B

I

BP-2007-11-150

An 80 year-old male with a ring-enhancing right basal ganglia lesion.

Cerebral pheohypomycosis.

B

I

BP-2007-06-141

A 55 year-old man with liver failure, delirium and seizures.

Neurosarcoidosis.

B

I

BP-2007-06-140

Leg weakness after liver transplant.

Coccidioidal granulomatous meningitis and abscesses.

B

I

BP-2006-11-128

A 39-year-old man with new onset seizures.

Intracerebral tuberculoma.

B

I

BP-2006-02-119

A 49-year-old man with neuropsychiatric symptoms followed by progressive cognitive decline.

Sporadic Creutzfeldt-Jakob disease

B

I

BP-2004-09-102

Young girl with headache and stiff neck.

Granulomatous amebic meningoencephalitis caused by Balamuthia mandrillaris.

B

I

BP-2004-07-100

A man in his 40s with headaches and dyspnea.

Cryptococcal meningitis and focal pneumonitis in a patient with pulmonary sarcoidosis.

B

I

BP-2004-01-094

A 74-year-old man with history of gastric carcinoma presented with partial-complex seizures.

Neurocysticercosis.

B

I

BP-2003-10-091

A 59-year-old woman with sudden onset of diplopia.

Listerial rhombencephalitis.

B

I

BP-2003-04-085

A 55-year-old diabetic male with progressive loss of sensitivity.

Toxoplasmosis.

B

I

BP-2002-12-081

A 19 year-old male with febrile illness after jet ski accident.

Primary amebic meningoencephalitis (Naegleria fowleri).

B

I

BP-2002-10-079

A 27 year-old female with epilepsy.

Rasmussen’s encephalitis.

B

I

BP-2000-05-050

A 35 year-old male with a left temporal lobe mass.

Cerebral toxoplasmosis.

B

I

BP-1998-07-028

A 21 year-old man with new-onset seizures and a temporal lobe mass.

Neurocysticercosis.

B

I

BP-1998-05-026

A 36 year-old male with HIV infection and multiple cranial neuritis.

Cytomegalovirus (CMV) ventriculo-encephalitis, polyradiculitis, and multiple cranial neuritis.

B

I

BP-1997-09-018

A 26 year-old woman with new onset seizure.

Progressive multifocal leukoencephalopathy (PML).

B

I

BP-1997-07-016

A 60 year-old diabetic male with transient ischemic attack.

Cryptococcal meningitis with vasculitis and cerebral infarct.

B

I

BP-1996-09-006

A 44 year-old woman with new brain lesion.

Acute demyelinating lesion consistent with multiple sclerosis.

B

NH

BP-2018-08-385

An 83 year-old woman CML and meningioma.

Myeloid sarcoma in CNS, as a blast transformation of chronic myelomonocytic leukemia (CMML), subdural hematoma, meningothelial meningioma (WHO Grade I).

B

NH

BP-2018-06-382

A 66 year-old woman with cognitive decline and weakness.

Lymphomatosis cerebri.

B

NH

BP-2018-04-378

A 72 year-old woman with hearing loss and intraventricular mass.

Primary CNS Lymphoplasmacytic Lymphoma.

B

NH

BP-2018-02-373

A 68 year-old woman with MS and worsening skin lesions.

CD8+ Cytotoxic T-Cell Lymphoma .

B

NH

BP-2018-01-371

A 24 year-old man with seizure and scalp lesion.

Spindle/sclerosing variant of follicular lymphoma.

B

NH

BP-2017-09-368

A 60 year-old woman with hypertension and infarcts.

Intravascular NK/T-cell lymphoma with associated multifocal microinfarcts.

B

NH

BP-2016-08-336

A 36 year-old female with facial sensory loss, headache, nausea and weight loss.

Multifocal intra-axial histiocytic sarcoma of the CNS, primary versus metastatic.

B

NH

BP-2016-02-326

A 22 year-old woman with retro-orbital pain.

Langerhans cell histiocytosis, retro-orbital.

B

NH

BP-2016-02-325

A 74 year-old woman with headache and weakness.

Histiocytic Sarcoma, intra-axial.

B

NH

BP-2015-11-319

A 30 year-old man with progressive visual field defect.

Isolated extracranial-intracranial myeloid sarcoma, monoblastic variant, cranial bone.

B

NH

BP-2015-01-300

A 35 year-old man with painful forehead swelling and lytic skull lesion.

Langerhans cell histiocytosis (LCH), cranium.

B

NH

BP-2014-10-294

A 24 year-old woman with vertigo, vomiting and posterior fossa lesion.

Natural killer (NK) cells lymphoblastic lymphoma/leukemia.

B

NH

BP-2014-10-293

A 44 year-old obese, male smoker with involuntary movements and intracranial lesion.

Marginal zone B-cell lymphoma (MALT lymphoma), dural base.

B

NH

BP-2014-09-292

A 77 year-old woman with headache and altered behavior.

Marginal zone B-cell lymphoma (MALT lymphoma), dural base.

B

NH

BP-2013-08-265

A 78 year-old man with dysphagia, cranial nerve palsies and posterior fossa mass.

Atypical plasma cell neoplasm, extra-axial, posterior fossa and jugular foramen.

B

NH

BP-2013-06-261

A 78 year-old male with gait disturbance.

Primary natural killer NK/T-cell lymphoma, nasal type, of the central nervous system, intra-axial parietal mass.

B

NH

BP-2013-02-252

A 29 year-old male with ring enhancing mass.

Intracerebral Langerhans histiocytosis.

B

NH

BP-2011-06-220

A 42 year-old woman with transient dizziness.

Intravascular large B cell lymphoma.

B

NH

BP-2009-11-198

A 76 year-old woman with paraplegia.

 

CNS spread of untreated acute myeloid leukemia associated with acute demyelination.

B

NH

BP-2009-09-195

A 61 year-old man with wide-based gait.

Tumor-like deposits of κ light chain surrounded by mature kappa chain-expressing plasma cells.

B

NH

BP-2009-05-186

A 76 year old man with cognitive and neurological symptoms.

T-cell lymphoma, cerebral.

B

NH

BP-2009-03-182

A 46 year-old female with 5 month history of numbness in her toes.

CNS manifestation of multiple myeloma.

B

NH

BP-2009-03-183

A 69 year-old man with left hemispheric necrotizing mass lesion.

EBV-associated diffuse large B cell lymphoma and additional microglial nodule encephalitis of the brainstem with associated severe hypoxic injury of neurons.

B

NH

BP-2007-12-152

A 51 year-old female with double vision.

Diffuse large B-cell lymphoma arising within a ganglioglioma of the cerebellum.

B

NH

BP-2007-08-144

A year-old woman with a clival mass.

Langerhans cell histiocytosis, unifocal, clivus.

B

NH

BP-2006-08-125

A 64 year-old woman with dementia and leukoencephalopathy.

Lymphomatosis cerebri.

B

NH

BP-2006-06-123

An 80-year-old female with neuropsychiatric changes.

Angiotropic (intravascular) lymphoma and cerebrovascular beta-amyloidosis.

B

NH

BP-2005-09-114

A 43 year-old woman with a temporal mass.

Granulocytic sarcoma, intracerebral.

B

NH

BP-2005-06-111

A 62-year-old man with chronic pyothorax.

Pyothorax-associated lymphoma.

B

NH

BP-2004-10-103

A man in his late-40s with progressive dementia.

Diffuse large B-cell lymphoma.

B

NH

BP-2003-01-082

A 56-year-old woman with right frontal tumor of the dura.

Marginal zone B-cell lymphoma (MALT lymphoma), dural based.

B

NH

BP-2002-11-080

A 72 year-old woman with a pineal gland mass.

High-grade non-Hodgkin’s B-cell lymphoma involving the pineal and retroperitoneum.

B

NH

BP-2002-02-071

A 29 year-old woman with a skull mass for two months

Langerhans cell histiocytosis, cranium.

B

NH

BP-1999-10-043

A 70-year-old female with seizures and progressive dementia.

Intravascular lymphoma.

B

NM

BP-2019-12-418

A 65 year-old man with sudden hemiplegia.

Choriocarcinoma, likely metastatic.

B

NM

BP-2017-11-366

A 39 year-old man with hematuria, headache and blurred vision.

Metastatic chromophobe renal cell carcinoma in cerebellum.

B

NM

BP-2017-11-365

A 40 year-old woman with recent onset headache and spinal masses.

Metastasis of a gastrointestinal stromal tumor (GIST).

B

NM

BP-2016-04-329

A 66 year-old man with previous prostate cancer and sphenoid wing tumor.

Extra-osseous intracranial metastasis from prostatic carcinoma.

B

NM

BP-2015-08-314

A 59 year-old man with disseminated lung carcinoma and abnormal posterior fossa.

Dandy-Walker-Malformation. Mature midline posterior fossa teratoma. Metastatic lung adenocarcinoma to the right cerebellar hemisphere.

B

NM

BP-2015-06-309

A 55 year-old Brazilian man with acute onset lower limb weakness and Guillain-Barré syndrome.

Leptomeningeal amelanotic melanomatosis and brain metastases from gastric melanoma.

B

NM

BP-2014-08-289

A 53 year-old woman with headache and vomiting.

Intracranial tumor-to-tumor metastasis: Metastatic pulmonary adenocarcinoma to a diffuse astrocytoma (WHO grade II).

B

NM

BP-2012-07-238

A 76 year-old man with gait disturbance.

Balloon cell melanoma, metastatic to cerebellum.

B

NM

BP-2011-02-215

A 57 year-old woman with recurrent nausea and vomiting.

Metastatic leiomyosarcoma, cerebellum.

B

NM

BP-2010-06-206

A Posterior fossa lesion 45 years after ocular trauma.

Epithelioid and spindle cell conjunctival melanoma and metastatic epithelioid and spindle cell conjunctival melanoma.

B

NM

BP-2009-11-199

A 41 year-old woman with von Hippel-Lindau and a cerebellar Lesion

Clear cell renal cell carcinoma metastatic to illary hemangioblastosma in the setting of von Hippel- Lindau disease.

B

NM

BP-2008-12-176

A 72 year old man with new seizure while dancing.

Metastatic clear-cell type of renal carcinoma in a meningothelial meningioma.

B

NM

BP-2008-02-157

A 70 year-old man with enlarged pineal gland.

Solitary pineal metastasis of prostate adenocarcinoma with changes of secondary acute hydrocephalus.

B

NM

BP-2001-01-058

A year-old man with a history of Hodgkin’s disease.

Metastatic Hodgkin’s disease.

B

NN

BP-2020-01-419

A 8 year-old girl with headache and fourth ventricular mass

First, second, and fourth resection: Posterior fossa Ependymoma (WHO grade III; Methylation subgroup A); Malignant glioma, corresponding to glioblastoma (WHO grade IV), most likely radiation induced

B

NN

BP-2019-10-414

A 4 year-old girl with hemiparesis and ataxia.

Diffuse glioma, H3K27M-mutant, thalamus.

B

NN

BP-2019-10-413

A 58 year-old man with headache and temporal parietal mass.

Anaplastic pilomyxoid astrocytoma.

B

NN

BP-2019-04-402

A 39 year-old man with seizure and visual impairment.

Diffuse, Grade II astrocytoma, IDH-mutant, 1p/19q-intact, anaplastic, Grade III oligoastrocytoma (OA) with a dual genotype.

B

NN

BP-2019-02-398

A 8 year-old girl with headache and ‘heartbeat’ eyelid movements and loss of consciousness.

Angiocentric Glioma.

B

NN

BP-2019-01-396

A 25 year-old man with gait disturbance.

Anaplastic ependymoma (WHO Grade III) with neuropil-like islands.

B

NN

BP-2018-12-393

A 82 year-old man with 3 months of cognitive decline.

Meningioma with iron-positive macrophages (pseudo-pigmentation).

B

NN

BP-2018-10-390

A 44 year-old woman with 2 weeks of headache.

Clear cell ependymoma, WHO grade II.

B

NN

BP-2018-06-381

A 77 year-old man with tremor and gait problems.

Diffuse glioma exhibiting growth and invasion pattern of gliomatosis cerebri.

B

NN

BP-2018-04-377

A 9 year-old girl with hemiplegia, headache and vomiting.

Anaplastic astrocytoma of the pons/ WHO Grade III (DIPG) (H3K27M mutation was not checked)

B

NN

BP-2018-02-374

A 37 year-old woman with blurred vision and hemianopia.

Atypical Teratoid/Rhabdoid Tumor.

B

NN

BP-2017-08-361

A 8 year-old girl with headaches, vomiting and deep seated mass.

Small Cell Astrocytoma (H3K27M mutant, it should be now classified as diffuse midline glioma with H3K27M mutation), mass in basal ganglia and medial temporal lobe.

B

NN

BP-2017-04-353

A 19 year-old male with narcolepsy and dural masses.

Disseminated oligodendroglial-like leptomeningeal tumor with malignant (anaplastic) transformation.

B

NN

BP-2016-09-340

A 55 year-old woman headaches and leptomeningeal pigmentation

Diffuse leptomeningeal melanocytoma with no BRAF mutation.

B

NN

BP-2016-04-330

A 32 year-old man with headaches and vascular lesion in temporal region.

Arteriovenous malformation associated with anaplastic astrocytoma.

B

NN

BP-2016-03-328

A 59 year-old woman with headache and retrosellar mass.

Atypical extra-ventricular ganglioneurocytoma.

B

NN

BP-2015-12-322

A 14 year-old boy with headache and seizure.

Atypical teratoid rhabdoid tumor.

B

NN

BP-2015-11-320

A 34 year-old man with headaches, confusion and hemiparesis.

Glioblastoma with primitive neuroectodermal (PNET) features and metastasis of the PNET component, frontal-temporal-parietal mass.

B

NN

BP-2015-09-315

A 74 year-old man with hearing loss, imbalance and hand numbness.

Schwannoma, jugular foramen.

B

NN

BP-2015-04-306

41 year-old male with long history of seizures and subcortical parietal lesion.

Angiocentric glioma, WHO grade I.

B

NN

BP-2015-02-301

A 11 year-old boy who sustained head injury after episode of vertigo and visual disturbance.

Anaplastic ependymoma (WHO grade III) with granular cell features.

B

NN

BP-2015-01-299

A 64 year-old woman admitted with fatigue, headache, and weight loss.

Primary diffuse leptomeningeal gliomatosis (PDLG) (WHO grade III).

B

NN

BP-2014-04-281

A 26 year-old woman with visual disturbance prepontine mass.

Medulloblastoma, desmin positive, with drop metastases.

B

NN

BP-2014-03-279

Two cases of intraventricular haemorrhage.

Central neurocytoma, WHO grade II, complicated by hemorrhage.

B

NN

BP-2014-03-278

A 6 year-old girl with headache, vomiting and syncope and large parietal mass.

Malignant peripheral nerve sheath tumor, parietal extra-axial mass.

B

NN

BP-2014-02-277

A 56 year-old man with congenital heart disease and ring enhancing cerebral lesions.

Granular cell astrocytoma.

B

NN

BP-2013-12-274

A 72 year-old woman with back pain and spinal mass.

Intradural melanocytoma, spinal cord.

B

NN

BP-2013-11-270

A 49 year-old woman with ovarian tumor and pineal mass.

Papillary tumor of the pineal region, WHO grade II-III.

B

NN

BP-2013-10-268

A 26 year-old man with memory loss and lethargy.

Chordoid glioma of the third ventricle, WHO grade II, mass in third ventricle and lateral ventricle, midline.

B

NN

BP-2013-06-260

A 30 year-old male with headaches.

Anaplastic central neurocytoma, septum pellucidum and bilateral lateral ventricles.

B

NN

BP-2013-05-258

An 8 year-old male with headaches and vomiting.

Glioblastoma, WHO grade IV, with extensive neuronal differentiation.

B

NN

BP-2013-03-255

A 29 year-old male with seizures.

Anaplastic oligodendroglioma, WHO grade III.

B

NN

BP-2013-01-251

A 24 year-old female with MS and intracranial mass.

Hybrid peripheral nerve sheath tumor, with schwannoma/perineurioma components.

B

NN

BP-2013-01-250

A 40 year-old male with vertigo and headaches.

Combined tanycytic ependymoma and subependymoma, (WHO grade II).

B

NN

BP-2012-12-248

A 30 year-old male with headache, hearing impairment and blackout.

Schwannoma with exuberant inflammatory infiltrate and intratumoral edema that may have caused the increase of mass effect and sudden clinical deterioration.

B

NN

BP-2012-09-242

A 26 year-old male with difficulty in walking, diplopia and unilateral shaking.

Medulloblastoma, WHO Grade IV, with divergent differentiation including myoblastic, glial, osteoblastic and chondroblastic differentiation.

B

NN

BP-2012-07-239

A 14 year-old girl with sciatica and ataxia.

Multicentric pleomorphic xanthoastrocytoma (PXA; WHO grade II) with leptomeningeal dissemination.

B

NN

BP-2012-02-229

A 23 year-old man with seizures and cystic lesion.

Pigmented (melanin producing) desmoplastic ganglioglioma.

B

NN

BP-2012-01-226

A 4 month-old with vomiting, seizures and large cerebral mass.

Cystic atypical choroid plexus papilloma, WHO grade II.

B

NN

BP-2011-12-225

A 45 year-old man with pineal region tumor.

 

Papillary tumor of the pineal region (2007 WHO Classification assigns a Grade II to III).

B

NN

BP-2011-08-221

A 71 year-old woman with headache and proptosis.

Primary extradural meningioma, intraosseous type, WHO Grade I.

B

NN

BP-2011-07-219

A 58 year-old man with phacomatosis, tinnitus, deafness and headaches.

Schwannoma grade I WHO of the jugular foramen associated with leptomeningeal blue nevus.

B

NN

BP-2011-04-217

A 2 year-old boy with imbalance and strabismus.

Medulloblastoma with rhabdomyoblastic differentiation ("medullomyoblastoma").

B

NN

BP-2011-01-214

A 16 month-old girl with fever, hypoxia and seizures.

Congenital intraventricular atypical meningioma and neurofibromatosis 2 (NF2).

B

NN

BP-2010-09-210

A 3 year-old girl with altered mental status, gait difficulty and vomiting.

Embryonal tumor with abundant neuropil and true rosettes (ETANTR).

B

NN

BP-2010-08-209

A 17 year-old girl with headache and complex partial seizure.

Extra-axial anaplastic ependymoma.

B

NN

BP-2010-05-207

A 35 year-old man with falcine tumor.

Primary intracranial solitary leptomeningeal astrocytoma (WHO grade III).

B

NN

BP-2010-04-205

A 81 year-old male with confusion and weakness.

 

Glioblastoma (WHO grade IV) with primitive neuroectodermal tumor (PNET)-like component.

B

NN

BP-2010-01-202

A 12 year-old boy with multiple brain masses.

#1 - Anaplastic medulloblastoma, #2 - Low-grade lipoastrocytoma, #3 - Pilocytic astrocytoma with radiation induced modification.

B

NN

BP-2009-10-197

A 25 year-old woman with a mass in the hippocampus.

Angiocentric glioma in the hippocampus.

B

NN

BP-2009-09-194

A 6 year-old with an extra-axial mass.

Atypical meningioma associated with reactive hyperplasia and colonization of meningeal melanocytes.

B

NN

BP-2009-05-187

A 22 year-old man with intracranial hypertension.

Primary diffuse leptomeningeal primitive neuroectodermal tumor (PDL PNET).

B

NN

BP-2009-04-184

A 6 year-old girl with hydrocephalus.

Pediatric tectal glioma with focal anaplasia.

B

NN

BP-2008-12-177

A 15 year-old boy with a posterior fossa tumor.

Pigmented pleomorphic xathoastrocytoma.

B

NN

BP-2008-11-175

A 2 year-old girl with a posterior fossa tumor.

Embryonal Tumor with Abundant Neuropil and True Rosettes (ETANTR).

B

NN

BP-2008-11-174

A 12 year-old boy with a posterior fossa tumor.

Glioblastoma multiforme, WHO grade IV.

B

NN

BP-2008-10-173

A 33 year-old Chinese woman with a left frontal lobe tumor.

Astroblastoma.

B

NN

BP-2008-10-172

A 32 year-old man with a fourth ventricular mass.

Intraventricular astrocytoma with extensive lipidization (lipoastrocytoma).

B

NN

BP-2008-09-171

A 16 year-old male with cerebellar mass.

Cerebellar pleomorphic xanthoastrocytoma.

B

NN

BP-2008-09-170

A 28 year-old man with headache and aphasic speech and visual disturbances.

Pleomorphic xanthoastrocytoma with anaplastic features (WHO grade III) rapidly progressing towards pleomorphic xanthoastrosarcoma (WHO grade IV).

B

NN

BP-2008-06-164

A 50 year-old woman with pigmented tumor of the 4th ventricle.

Primary CNS melanocytic tumor of intermediate type progressing to metastatic melanoma.

B

NN

BP-2008-05-161

Recurrent cerebellar lesion in a young boy.

Cerebellar neurocytoma.

B

NN

BP-2008-03-159

A 2 year-old girls with right leg weakness.

Glioblastoma multiforme, WHO grade IV.

B

NN

BP-2008-03-158

A 44 year-old man with abnormal gait.

Choroid plexus papilloma, oncocytic variant.

B

NN

BP-2007-10-146

A 72 year-old woman with right frontal mass.

Plasma cell predominant lymphoplasmacytic-rich meningioma, grade I (WHO), with crystalline inclusions.

B

NN

BP-2007-09-148

A 21 month old child with acute spastic paraparesis

Stroma poor ganglioneuroblastoma of sympathetic ganglion.

B

NN

BP-2007-07-143

A 49 year-old female with history of head trauma.

Infiltrating meningioma.

B

NN

BP-2007-07-142

A 43 year-old Chinese man with retro-orbital mass.

Cellular schwannoma, orbit.

B

NN

BP-2007-05-139

A 15 year-old girl with cystic tumor.

Pleomorphic xanthoastrocytoma with anaplastic features.

B

NN

BP-2007-03-135

A 40 year-old male with history of brain tumor 10 years ago.

1992 diagnosis: astrocytoma, WHO grade II, BP-2002- diagnosis: primitive neuroectodermal tumor (PNET), WHO grade IV.

B

NN

BP-2007-02-133

A 30-year-old man with tuberous sclerosis.

Subependymoma giant cell astrocytoma with malignant phenotype and axial spread.

B

NN

BP-2007-02-132

A 35-year-old woman with dural-based mass.

Pleomorphic xanthoastrocytoma.

B

NN

BP-2007-01-131

A 76 year-old woman with recent bladder cancer and new brain lesion.

Diffuse high-grade glioma.

B

NN

BP-2006-12-129

A 37 year-old pregnant woman with new onset seizures.

Myxoid meningioma.

B

NN

BP-2006-10-127

A 37-year-old male with headache.

Low-grade astroblastoma, cerebellum.

B

NN

BP-2006-09-126

A 42 year-old man with a densely vascular spinal mass.

De novo malignant ganglioglioma of the spinal cord with unusually prominent dysplastic vessels (“malignant angio-ganglioma”).

B

NN

BP-2006-05-122

A 57-year-old female with a benign tumor in the ethmoid sinus.

Olfactory neurocytoma.

B

NN

BP-2006-04-121

A 4-year-old girl with mass in the frontotemporal bone.

Melanotic neuroectodermal tumor of infancy.

B

NN

BP-2006-03-120

A 21-year-old female with a cystic brain lesion.

Gangliocytoma, intracerebral.

B

NN

BP-2005-12-117

A 19-year-old male with generalized seizures, unconsciousness and a deviation of gaze.

Light chain deposition disease of the brain following low-grade lymphoma.

B

NN

BP-2005-11-116

A 35-year-old woman with progressive bilateral leg weakness.

Intermediate grade melanocytoma, spinal cord.

B

NN

BP-2005-08-113

A 45 year-old male with symptomatic mass in the frontal lobe.

Oligodendroglioma, WHO grade II with neurocytic differentiation.

B

NN

BP-2005-07-112

A 21-year-old female with a third ventricular tumor.

Intraventricular schwannoma, WHO grade I.

B

NN

BP-2005-04-109

Woman aged 24 years with fourth ventricular mass.

Giant cell ependymoma.

B

NN

BP-2005-02-107

A 10-month-old boy with a large pineal tumor.

Pineal anlage tumor without immature components.

B

NN

BP-2005-01-106

A 7-year-old boy with midline cerebella mass.

Primitive neuroectodermal tumor (PNET) showing multilineal differentiation.

B

NN

BP-2004-12-105

A 1 year-old girl with an aggressive skull tumor.

Malignant melanotic neuroectodermal tumor of infancy involving the brain, cranial bone and scalp.

B

NN

BP-2004-06-099

A male in his late 60s with recurrent extracerebral tumor.

Recurrent pure rhabdoid meningioma evolving from a transitional meningioma with rhabdoid-like tumor areas.

B

NN

BP-2004-03-096

A 24-year-old woman with a one-year history of bifrontal headaches.

Extraventricular neurocytoma.

B

NN

BP-2003-12-093

A 70-year-old woman with a recurrent meningeal mass.

Recurrent meningioma with rhabdomyosarcomatous differentiation.

B

NN

BP-2003-11-092

Neonatal female with congenital brain tumor.

Gemistocytic astrocytoma, congenital.

B

NN

BP-2003-09-090

A 79 year-old woman with right frontal lobe mass.

Gliosarcoma.

B

NN

BP-2003-06-087

A 33-year-old male with a long history of epilepsy.

Meningioma and meningioangiomatosis.

B

NN

BP-2002-09-078

A 24 year-old female with a parietal occipital tumor.

Papillary glial neuronal tumor

B

NN

BP-2002-08-077

A 21 year-old male with cystic intracerebral tumor.

Schwannoma, intracerebral.

B

NN

BP-2002-06-075

A 57 year-old male with leptomeningeal and liver tumors.

Metastatizing, melanocytic leptomeningeal tumor with histomorphological characteristics of a melanocytoma.

B

NN

BP-2002-03-072

A 28 year-old woman with neck and back pain.

Plexiform neurofibroma, facial nerve.

B

NN

BP-2001-09-066

A 51  year-old man with seizures since childhood.

Ganglioglioma with neurofibrillary tangles.

B

NN

BP-2001-04-061

A year-old woman with gait disorders.

Meningothelial meningioma with lipomatous and rhabdoid differentiation.

B

NN

BP-2001-03-060

A year-old female with a cerebellar mass.

Lhermitte-Duclos disease (dysplastic gangliocytoma of the cerebellum).

B

NN

BP-2000-12-057

A 16 year-old boy with 2-week history of progressive lethargy.

Desmoplasmic infantile ganglioglioma, WHO grade I.

B

NN

BP-2000-04-049

A 43 year-old male with generalized epileptic seizures.

Lymphoplasmacyte-rich meningioma, WHO grade I.

B

NN

BP-2000-03-048

A 5 month-old boy with occipital bone mass.

Melanotic neuroectodermal tumour of infancy.

B

NN

BP-2000-01-046

A 12-year-old boy with recent onset seizures.

Extraventricular atypical neurocytic neoplasm ("cystic ganglioneurocytoma").

B

NN

BP-1999-06-039

A 22-year-old female with intraventricular mass.

Choroid plexus carcinoma.

B

NN

BP-1999-05-038

A 16-year-old male with history of low-grade astrocytoma.

Pilocytic astrocytoma, WHO grade I, with widespread dissemination in the CNS.

B

NN

BP-1999-01-034

A29 week-gestational age newborn with echogenic mass in third ventricle.

Primitive neuroectodermal tumor (PNET), congenital.

B

NN

BP-1998-10-031

A 61 year-old male with brain tumor and oral, lung, and palpebral masses.

Gliosarcoma with selective extraneural sarcoma metastases.

B

NN

BP-1998-09-030

An 18 year-old male with large cystic orbital tumor.

Pilocytic astrocytoma with cystic degeneration and evidence of old and fresh hemorrhage, orbit.

B

NN

BP-1998-08-029

A 45 year-old man with headache, ataxia, and impairment of the state of balance.

Pineocytoma with neuronal differentiation, WHO grade II.

B

NN

BP-1997-06-015

A 42 year-old man with left facial weakness.

Malignant epithelioid schwannoma, trigeminofacial nerve.

B

NN

BP-1997-05-014

A 31 year-old woman with seizures, fatigue and attention deficits.

Dysembryoplastic neuroepithelial tumor (DNET).

B

NN

BP-1997-03-012

A 4 year-old girl with ring chromosome 22 and brain tumor.

Atypical teratoid/rhabdoid tumor with ring chromosome 22.

B

NN

BP-1997-02-011

A 9 year-old girl with nausea, vomiting and hydrocephalus.

Anaplastic ependymoma, WHO grade III.

B

NN

BP-1996-12-009

A 22 month-old girl with a cervicomedullary mass.

Pilocytic astrocytoma with focal palisading features of formerly “primitive polar spongioblastoma”

B

NN

BP-1996-08-005

An 11 year-old girl with frontal lobe tumor.

Central neurocytoma.

B

NN

BP-1996-07-004

A 4 year-old girl with precocious puberty.

Hypothalamic hamartoma.

B

NN

BP-1996-05-002

A 9 month-old infant with hydrocephalus.

Pigmented choroid plexus papilloma.

B

NO

BP-2019-11-416

A 21 month-old male with cerebellar mass.

Germinoma.

B

NO

BP-2019-08-410

A 55 year-old man with speech and behavioral change.

High-grade intracerebral myxofibrosarcoma, intra-axial.

B

NO

BP-2019-06-406

A 41 year-old woman with headache and dizziness.

Meningeal solitary fibrous tumor/hemangiopericytoma with ectopic salivary gland tissue.

B

NO

BP-2019-06-405

A 43 year-old man with scalp swelling.

Primary intracranial leiomyosarcoma arising from the dura.

B

NO

BP-2019-02-397

A 50 year-old man with diabetes, hypertension and hypothalamic ,mass.

Hemangioblastoma of the hypothalamus.

B

NO

BP-2019-01-395

A 36 year-old woman with ptosis.  

Epithelial-Myoepithelial Cell Carcinoma (EMCC)

B

NO

BP-2018-10-389

A 15 month-old boy with cerebellar mass.

Yolk sac tumor, cerebellum.

B

NO

BP-2018-09-388

A 63 year-old woman with mass on forehead.

Low-grade central osteosarcoma.

B

NO

BP-2018-01-372

A 74 year-old woman with head injury and intracranial lesion.

Intracranial low-grade fibromyxoid sarcoma.

B

NO

BP-2017-09-367

A 72 year-old man with gait disturbance, headache and pineal mass.

Solitary fibrous tumor (SFT) of the pineal region.

B

NO

BP-2017-02-348

A 50 year-old man with presumed meningiomas.

Angiomyxofibroma, dural based intra-cerebral.

B

NO

BP-2017-02-347

A 19 year-old male with blurred vision, headache and large lobulated occipital mass.

Intracerebral Chondroma.

B

NO

BP-2017-01-350

A 36 year-old man with multiple meningiomas and nasal mass.

Olfactory neuroepithelioma.

B

NO

BP-2016-12-345

A 3 year-old boy with progressive hemiparesis and thalamic tumor.

Gossypiboma (Textiloma) and residual pilocytic astrocytoma WHO grade I.

B

NO

 BP-2016-12-344

A 65 year-old woman with facial pain and CP angle tumor.

Epidermoid Cyst with Malignant Transformation to Squamous Cell Carcinoma.

B

NO

BP-2016-11-343

A 49 year-old woman with dysphagia and foramen magnum lesion.

Myopericytoma, cranial base.

B

NO

BP-2016-01-324

A 12 year-old boy with progressive hemiparesis.

Germinoma, thalamus and cerebral peduncle.

B

NO

BP-2015-09-316

A 2 year-old girl with large parieto-occiptal mass.

Malignant myoepithelioma with extensive leptomeningeal spread to the cervical, thoracic and lumbar spine.

B

NO

BP-2015-06-310

A 19 year-old man with headache, neck stiffness and hemiparesis.

Disseminated anaplastic hemangiopericytoma WHO grade III / solitary fibrous tumor, cellular type.

B

NO

BP-2015-04-305

A 40 year-old female with headache, vomiting and superficial lesions in brain.

Primary leptomeningeal sarcomatosis.

B

NO

BP-2015-02-302

A 43 year-old woman with 6 months of nausea and vomiting causing significant weight loss, followed by ataxia and nystagmus.

Histiocytic sarcoma, multifocal, intra-axial and periventricular

B

NO

BP-2014-11-296

A 59 year-old woman with nausea, vomiting and cerebellopontine area mass.

Malignant Triton tumor (High-grade malignant peripheral nerve sheath tumor with rhabdomyosarcomatous differentiation), cerebellopontine angle.

B

NO

BP-2014-11-295

A 37 year-old woman with headache, weakness and ventricular mass.

Intracranial solitary fibrous tumor with atypical histologic features (hemangiopericytoma) and distant bone metastases.

B

NO

BP-2014-04-280

A 40 year-old woman with sudden onset headache.

Lipomatous hemangiopericytoma (Fat forming solitary fibrous tumor) associated with oncogenic osteomalacia, mass in cranial base.

B

NO

BP-2013-09-266

A 42 year-old man with new onset seizures and well circumscribed temporal lobe mass.

Benign fibrous tumor (fibroma), extra-axial parietal.

B

NO

BP-2013-07-263

A 73 year-old male with progressive tetraparesis.

Giant cell-rich solitary fibrous tumor, extra-axial dorsal lower medullar mass.

B

NO

BP-2013-05-259

A 59 year-old female with neck and arm pain.

Inflammatory myofibroblastic tumor, extra-axial posterior fossa.

B

NO

BP-2013-04-257

A 68 year-old male with hearing loss.

Fetal type myxoid rhabdomyoma of the vestibular nerve.

B

NO

BP-2012-12-249

A 47 year-old woman with headache, visual and swallowing difficulties.

Chondroma of cerebellopontine angle.

B

NO

BP-2012-10-245

A 64 year-old woman with anosmia.

Sinonasal undifferentiated carcinoma.

B

NO

BP-2012-09-243

A 18 year-old woman motor cyclist who crashed with a subdural mass.

Chondrona of dural convexity.

B

NO

BP-2011-09-222

A 48 year-old man with vascular disease, vertigo, tinnitus, diplopia and ataxia.

Metastatic hemangioblastoma (disseminated hemangioblastomatosis).

B

NO

BP-2010-12-213

A 47 year-old man with lower extremity weakness.

Low- grade myofibroblastic sarcoma, right frontal lobe.

B

NO

BP-2010-11-212

A 56 year-old woman with headache.

Chondromyxoid fibroma, sphenoid bone.

B

NO

BP-2009-06-189

A 58 year old woman with a corpus callosum nodule at autopsy.

Lipoma of the Corpus Callosum.

B

NO

BP-2009-06-188

A 47 year-old male with a cerebellopontine angle tumor.

Angiolipomatous hamartoma of the cochlear nerve.

B

NO

BP-2009-02-181

A 64 year-old man with atypical cerebral lesions.

Angiosarcoma, cerebral.

B

NO

BP-2009-02-180

A 5 year-old male with interhemispheric frontal mass.

Encephalic lipoma (tubulonodular type) with neuroglial component associated with partial agenesis of the corpus callosum.

B

NO

BP-2009-01-178

A 5 year-old boy with a clival mass.

Epithelioid sarcoma.

B

NO

BP-2008-08-169

A 59 year-old male with sellar mass.

Pituitary gonadotroph adenoma with adamantinomatous craniopharyngioma.

B

NO

BP-2008-01-155

A 23 year-old Hispanic male with new onset seizures.

Masson's tumor (papillary endothelial hyperplasia), intracerebral.

B

NO

BP-2007-08-145

A 40 year-old woman with a progressive periventricular white matter lesion.

Diffusely infiltrating germinoma.

B

NO

BP-2007-04-136

A 57-year-old man with a dural-based parietal lobe tumor.

Supratentorial hemangioblastoma.

B

NO

BP-2007-01-130

A 27 year-old female with cranial nerve dysfunction.

Chondroblastoma, petrous portion of the temporal bone.

B

NO

BP-2004-02-095

A 44-year-old man with a 2-year history of epistaxis.

Paraganglioma, nasopharyngeal.

B

NO

BP-2003-08-089

A 47-year-old-woman with a 7-year-history of osteomalacia and hypophosphatemia.

Phosphaturic mesenchymal tumor (mixed connective tissue variant) of the cavernous sinus.

B

NO

BP-2003-02-083

A 53-year-old male with new onset seizures.

Osteochondroma, intra-cranial.

B

NO

BP-2002-07-076

A 66 year-old female with a one-year history of progressive left proptosis.

Solitary fibrous tumor, orbit.

B

NO

BP-2001-06-063

A year-old female with progressive confusion lethargy and headaches.

Malignant solitary fibrous tumor, intra-cranial dural based.

B

NO

BP-2000-06-051

A 68 year-old woman with a history of progressive hearing loss.

Endolymphatic sac tumor clinically mimicking jugular paraganglioma.

B

NO

BP-1999-04-037

A 44-year-old man with a bleeding intracerebral tumor.

Primary embryonal rhabdomyosarcoma of the brain, intra-axial.

B

NO

BP-1999-03-036

A 26-year-old male with a history of AIDS.

Leiomyoma associated with EBV, skull base.

B

NO

BP-1997-11-020

A 41 year-old female with a dura based occipital mass

Solitary fibrous tumor, dural based.

B

U

BP-2018-09-387

A 33 year-old woman with head and neck pain for 5 years.

Calcifying pseudoneoplasm of the neuraxis (CAPNON), cerebellopontine angle.

B

U

BP-2018-08-386

A 39 year-old woman with fever and headache for 9 months.

Chordoid meningioma with Castleman Syndrome.

B

U

BP-2018-07-384

A 72 year-old woman with progressive confusion and dural masses.

Erdheim-Chester Disease

B

U

BP-2018-07-383

A 43 year-old woman with headache and subarachnoid hemorrhage.

CNS Rosai-Dorfman disease with extensive meningeal and parenchymal involvement, and thrombosis in the venous sinuses followed by secondary multiple hemorrhagic infarcts.

B

U

BP-2018-03-375

A 36 year-old man with solvent exposure, headache and fever.

Inflammatory Amyloid Angiopathy and leptomeningeal amyloidosis with inflammation.

B

U

BP-2017-10-364

A 44 year-old woman with familial Mediterranean fever and cardiac arrest.

Systemic amyloid A (AA) amyloidosis with amyloid deposition in the choroid plexus and pituitary gland.

B

U

BP-2017-10-363

A 68 year-old woman with sudden onset fluent aphasia.

Rosai-Dorfman meningeal disease with IgG4-related disease histological features.

B

U

BP-2017-03-351

A 11 year-old male with headache, cranial nerve palsy and spinal meningeal lesion on MRI.

Leptomeningeal melanocytosis in the context of neurocutaneous melanosis with NRAS mutation (Q61K).

B

U

BP-2017-01-349

A 61 year-old male with prolactinoma treated with cabergoline.

Nodular amyloidoma of the pituitary gland/skull base.

B

U

BP-2016-10-342

A 64 year-old man with seizure and extraaxial mass.

Dural based extranodal Rosai Dorfman disease.

B

U

BP-2016-08-337

A 71 year-old man with headache, visual disturbance and agraphia

Amyloidoma, cerebral.

B

U

BP-2014-05-284

A 67 year-old woman with back pain and intramedullary mass.

Tophaceous pseudogout, intradural and intramedullary mass.

B

U

BP-2014-05-283

A 31 year-old woman with neck pain and clival mass.

Calcifying pseudoneoplasm of the neural axis (CAPNON).

B

U

BP-2012-11-247

A 63 year-old woman with polycythaemia, vertigo, ataxia and weakness.

Rosai Dorfman disease and multiple sclerosis.

B

U

BP-2012-10-244

3 A 2 year-old male with fever and diahorrea. Previous subarachnoid haemorrahage followed by cognitive problems.

Cerebral multifocal intracerebral schwannosis.

B

U

BP-2012-05-234

A 3 year-old boy with drug-resistant seizures, naevi and lesion in uncus.

Neurocutaneous melanosis.

B

U

BP-2012-02-228

A 38 year-old woman with diabetes insipidus, headache and hemiplegia.

Intracranial xanthogranuloma.

B

U

BP-2011-05-218

A 37 year-old woman with deteriorating vision.

Multiple intracranial meningeal extramedullary hematopoiesis.

B

U

BP-2009-09-194

A 6 year-old with an extra-axial mass.

Atypical meningioma associated with reactive hyperplasia and colonization of meningeal melanocytes.

B

U

BP-2008-08-168

A 60 year-old female with extra-axial frontal mass.

Erdheim-Chester Disease.

B

U

BP-2008-07-166

A 51 year-old man with sudden unexpected death.

Acute subarachnoid and intraventricular hemorrhage secondary to acute hemorrhage within a choroid plexus xanthogranuloma.

B

U

BP-2008-02-156

An 8 year-old child with lesion in the lentiform nucleus.

Rosai-Dorfman disease, intracerebral.

B

U

BP-2006-06-123

An 80-year-old female with neuropsychiatric changes.

Angiotropic (intravascular) lymphoma and cerebrovascular beta-amyloidosis.

B

U

BP-2005-12-117

A 19-year-old male with generalized seizures, unconsciousness and a deviation of gaze.

Light chain deposition disease of the brain following low-grade lymphoma.

B

U

BP-2004-05-098

Newborn with intracranial mass.

Chronic intracerebral hemorrhage of unknown etiology with reactive changes of the surrounding brain tissue and focal extramedullary erythropoiesis.

B

U

BP-2003-06-087

A 33-year-old male with a long history of epilepsy.

Meningioma and meningioangiomatosis.

B

U

BP-2003-05-086

A 57-year-old woman with slurred speech.

Rosai-Dorfman disease, leptomeningeal.

B

U

BP-2002-05-074

A 38 year-old man and 69-year-old woman with dural based masses.

Destombes-Rosai-Dorfman Disease, dural based.

B

U

BP-2001-07-064

A year-old man with a temporal bone mass.

Giant cholesterol granuloma of the petrous portion of the temporal bone with a small component of coexistent cholesteatoma.

B

U

BP-2000-09-054

A 15 year-old girl with parietal lobe lesion.

Solitary juvenile xanthogranuloma, solitary brain involvement without skin involvement.

B

U

BP-1997-04-013

A 32 year-old man with mental status changes and a severe occipital headache.

Acute hemorrhagic leukoencephalopathy.

B

U

BP-1997-01-010

A 7 year-old girl with seizures.

Meningioangiomatosis.

B

V

BP-2017-04-354

A 32 year-old male with headache, visual loss and callosal lesion.

Neurotuberculosis with parenchymatous acute arteritis and cortical infarction.

B

V

BP-2016-09-339

A 78 year-old woman who became unrousable following a hip hemiarthroplasty.

Fat embolism leading to cerebral edema with tentorial and tonsillar herniation.

B

V

BP-2016-07-335

A 36 year-old male with pulsatile crainal mass developing after head injury.

Sinus pericranii - the final diagnosis was based on the clinical, radiological and histopathological findings.

B

V

BP-2016-04-330

A 32 year-old man with headaches and vascular lesion in temporal region.

Arteriovenous malformation associated with anaplastic astrocytoma.

B

V

BP-2013-04-256

A 29 year-old female with confusion and ataxia.

Moyamoya disease.

B

V

BP-2012-06-236

A 71 year-old woman with atypical Parkinson’s disease.

Parkinson disease and hypoxic-ischemic encephalopathy.

B

V

BP-2012-04-232

A 11 year-old girl with scoliosis and abnormal cerebral veins.

A diffuse paradoxical cerebral air embolism of cortical veins.

B

V

BP-2012-03-231

A 47 year-old male with HIV infection and hemiplegia.

Invasive aspergillosis of the CNS with secondary hemorrhagic infarcts and subarachnoid hemorrhage in a patient with AIDS.

B

V

BP-2010-07-208

A 54 year-old woman with a lesion compressing the medulla.

Wegener's granulomatosis of the meninges.

B

V

BP-2010-03-204

A 24 year-old male with headaches.

Idiopathic disseminated giant cell arteritis (GCA).

B

V

BP-2009-03-183

A 69 year-old man with left hemispheric necrotizing mass lesion.

EBV-associated diffuse large B cell lymphoma and additional microglial nodule encephalitis of the brainstem with associated severe hypoxic injury of neurons.

B

V

BP-2006-09-126

A 42 year-old man with a densely vascular spinal mass.

De novo malignant ganglioglioma of the spinal cord with unusually prominent dysplastic vessels (“malignant angio-ganglioma”).

B

V

BP-2004-05-098

Newborn with intracranial mass.

Chronic intracerebral hemorrhage of unknown etiology with reactive changes of the surrounding brain tissue and focal extramedullary erythropoiesis.

B

V

BP-1997-10-019

A 19 year-old male with frontal lobe tumor.

Cryptic arteriovenous malformation (AVM) with severe hemosiderosis of left frontal lobe of brain.

B

V

BP-1997-07-016

A 60 year-old diabetic male with transient ischemic attack.

Cryptococcal meningitis with vasculitis and cerebral infarct.

B

V

BP-1996-11-008

A 28 weeks gestational age premature baby with lethargy and coma.

Thrombosis of internal cerebral veins.

M

F

BP-2008-07-167

A 42 year-old man with Discoid lupus and progressive weakness.

Hydroxychloroquine myopathy.

M

F

BP-1999-02-035

A 54-year-old man with severe muscle weakness.

Acute necrotizing myopathy (rhabdomyolysis) secondary to lovastatin and niacin.

M

F

BP-1996-06-003

A 32 year-old woman with anorexia nervosa.

Myopathy with cytoplasmic bodies and multi-cores. These findings are most consistent with a congenital myopathy or ipecac (emetine) toxicity.

M

G

BP-2019-12-417

A 67 year-old man with dyspnoea, weakness and raised creatine kinase.

Amyloid myopathy and cardiac amyloidosis due to primary AL amyloidosis.

M

G

BP-2018-05-379

A 3 month-old boy with progressive weakness

Lipid storage myopathy.

M

G

BP-2017-07-360

A 31 year-old male with slowly progressive weakness.

Hereditary myopathy with early respiratory failure (HMERF).

M

G

BP-2015-05-307

A 2 month-old male with hypotonia and MTM1 gene mutation.   

X-linked myotubular myopathy.

M

G

BP-2014-06-285

A year-old man with proximal weakness and elevated creatine kinase.

Becker muscular dystrophy (BMD).

M

G

BP-2009-07-190

A 9 year-old female with progressive weakness.

Manifesting carrier of a dystrophinopathy with a duplication noted in exon 5-11 of the dystrophin gene. Her X-inactivation studies showed marked skewing, with 95% inactivation of the wild-type allele.

M

G

BP-1997-12-021

A 48 year-old woman with chronic myalgias after exercise.

McArdle’s disease (Glycogenosis type V, phosphorylase A deficiency)

M

I

BP-2018-11-391

A 45 year-old woman with progressive upper and lower extremity proximal weakness.

Anti-synthetase syndrome-associated myositis.

M

I

BP-2017-07-359

A 62 year-old female with muscle pain and rash.

Immune-mediated necrotizing myopathy, iNM or IMNM (Synonym: necrotizing autoimmune myopathy, NAM) Most likely anti-synthetase myopathy (ASM).

M

I

BP-2003-07-088

A 63-year-old female with muscular atrophy.

Macrophagic myofasciitis.

M

I

BP-1999-11-044

A 56-year-old woman with left facial numbness.

Nerve: Axonal degeneration with non-caseating granulomas and vasculitis. Muscle: Granulomatous myositis.

M

NH

BP-2018-05-380

A 77 year-old woman with polyneuropathy.

Myopathy secondary to intravascular large B-cell lymphoma (IVLBCL), non-germinal center subtype.

N

F

BP-1998-11-032

A 70 year-old woman with SLE, paraproteinemia and polyneuropathy.

Toxic polyneuropathy induced by hydrochloroquine.

N

I

BP-2005-05-110

A 71 year-old male with 4 decades of symptoms referable to both central and peripheral nervous system.

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) with onion bulb formation in hypertrophic nerves and co-existent multiple sclerosis (MS).

N

I

BP-1999-11-044

A 56-year-old woman with left facial numbness.

Nerve: Axonal degeneration with non-caseating granulomas and vasculitis. Muscle: Granulomatous myositis.

N

NH

BP-2016-07-338

A 49 year-old man with headache, weight loss and cranial nerve disturbances.

Segment of nerve involved by adult T cell leukemia/lymphoma (ATLL).

N

U

BP-1999-12-045

A 71-year-old woman with progressive sensori-motor polyneuropathy.

Paraproteinemic (IgM) polyneuropathy with features of widely spaced myelin, segmental demyelination, onion bulbs and axonal changes.

N

U

BP-1996-10-007

A 51 year-old woman with new rapidly progressive weakness.

Acute motor axonal neuropathy.

N

V

BP-1999-07-040

A 66-year-old man with a subacute multi-system disorder and polyneuropathy.

Microvasculitis associated with systemic lupus erythematosus (SLE).

O

NN

BP-2003-03-084

A 41-year-old woman with a solitary lesion in the liver.

Ectopic ependymoma of the liver.

P

F

BP-2001-11-068

A 67 year-old man in coma requiring prolonged mechanical ventilation.

Massive adenohypophysial necrosis (few weeks old) corresponding to "respirator pituitary".

P

I

BP-2012-03-230

A 28 year-old woman with amenorrhoea and visual disturbance.

Atypical pituitary adenoma with prominent lymphocytes infiltration and germinal centers.

P

I

BP-1998-02-023

An 82 year-old Caucasian male with progressive visual deficits.

Recurrent Pituitary Adenoma. Paranasal Sinus Contents with Fungal Elements, consistent with Microascus species.

P

MO

BP-2019-11-415

A 13 year-old girl with sellar mass.

 Germinoma.

P

NH

BP-2007-05-138

A 63 year-old man with dementia, ataxia and VI nerve palsy.

Intravascular large B-cell lymphoma with extensive sellar involvement.

P

NM

BP-2013-02-253

A 50 year-old male with back pain and diplopia.

Metastatic hepatocellular carcinoma.

P

NM

BP-2006-07-124

A man in his mid-70’s with a sellar mass.

Pituitary oncocytoma with metastatic malignant melanoma.

P

NN

BP-2019-07-408

A 79 year-old woman with headache and enlarging feet.

Pituitary gangliocytoma associated with acromegaly.

P

NN

BP-2017-08-362

A 39 year-old woman with visual deterioration and a suprasellar mass.

Sellar Melanocytoma.

P

NN

BP-2017-05-355

A 57 year-old female with hemianopia and suprasellar mass.

Granular cell tumor, neurohypophysis.

P

NN

BP-2016-12-346

A 47 year-old woman with headache, eye pain and lesion involving the cavernous sinus.

Atypical teratoid rhabdoid tumor (AT/RT), sellar mass with bone extension.

P

NN

BP-2016-01-323

A 55 year-old man with electrolyte disturbance and fatigue.

Spindle cell oncocytoma of adenohypophysis.

P

NN

BP-2015-10-318

A 48 year old with headache and hemianopia.

Spindle cell oncocytoma of the adenohypophysis.

P

NN

BP-2015-10-317

A 30 year-old woman with amenorrhoea and visual loss.

Pituicytoma (WHO Grade I).

P

NN

BP-2012-08-241

A 40 year-old woman with seizures and menstrual disorder.

Pituicytoma.

P

NN

BP-2008-05-160

59 year-old male with pan-hypopituitarism.

Pituicytoma.

P

NN

BP-2007-10-147

A 61 year-old man with hyponatremia.

Schwannoma, intrasellar.

P

NN

BP-2001-08-065

A 59 year-old woman with a sellar/suprasellar mass.

Atypical granular cell tumor of the neurohypophysis.

P

NO

BP-2019-07-407

Polyuria, polydipsia, headache and loss of consciousness.

Papillary craniopharyngioma with dysplastic changes.

P

NO

BP-2017-06-358

A 42 year-old male with AIDS presenting with confusion, headache and lethargy.

Germinoma, sellar area.

P

NO

BP-2017-06-357

A 42 year-old male with thyroiditis and diabetes insipidus.

 Germinoma, sellar area.

P

NO

BP-2017-05-356

A 54 year-old male with visual loss, facial pain and eye displacement.

Growth Hormone-secreting Pituitary Carcinoma.

P

NO

BP-2013-10-269

A 34 year-old man with intra and supra-sellar mass.

Embryonal rhabdomyosarcoma arising from the pituitary.

P

NO

BP-2012-08-240

A 33 year-old woman with headaches and visual loss.

 Paraganglioma, sellar region.

P

NO

BP-2012-04-233

A 52 year-old male with Cushings and recurrent sellar mass.

Pituitary adenoma, adenocorticotroph adenoma with Nelson’s syndrome.

P

NO

BP-2012-03-230

A 28 year-old woman with amenorrhoea and visual disturbance.

Atypical pituitary adenoma with prominent lymphocytes infiltration and germinal centers.

P

NO

BP-2008-07-191

A 59 year-old female with suprasellar mass.

Capillary hemangioma.

P

NO

BP-2007-09-149

A 35 year-old woman with intrasellar and suprasellar lesion

Concomitant sparsely granulated growth hormone cell pituitary adenoma and granulomatous giant cell hypophysitis with molecular pathological detection of M. tuberculosis DNA.

P

NO

BP-2002-01-070

A 59 year-old woman with an intrasellar lesion.

Intrasellar glioneuronal hamartoma with GH-cell pituitary adenoma and schwannoma-like component.

P

NO

BP-1999-08-041

A 49-year-old woman with visual disturbances.

Embryonal rhabdomysarcoma in the sella turcica.

P

NO

BP-1996-04-001

A 20 year-old with a pituitary tumor.

Germinoma.

P

U

BP-1998-12-033

A 16 year-old female with headaches, lethargy and a sellar/suprasellar mass.

Rathke's Cleft Cyst.

S

C

BP-2012-06-237

Developmental lesion overlying spine.

Pacinian hyperplasia ("Pacinioma", pacinian neuroma) associated with meningoradiculocele.

S

C

BP-1998-06-027

A 2 year-old boy with lumbosacral mass.

Lipomyelomeningocele with nephrogenic rests.

S

D

BP-2001-12-069

A 25 year-old woman with progressive weakness during pregnancy.

Motor neuron disease with basophilic inclusions.

S

G

BP-2013-09-267

A 79 year-old man with Parkinsonism, back pain, leg weakness and urinary dysfunction.

Gaucher disease Type I, bone of vertebral column.

S

G

BP-2000-02-047

A 77 year-old man with dementia, motor dysfunction, and liver disease.

Acquired (Non-Wilsonian) hepatocerebral degeneration with "shunt myelopathy".

S

I

BP-2015-03-304

33 year old with lesion in cervical cord.

Necrotizing myelopathy possibly related to the group defined as neuromyelitis optica spectrum disorders (NMOSD).

S

I

BP-2009-12-201

A 10-year-old girl with neck pain.

Neuromyelitis optica.

S

MM

BP-2019-05-404

A 62 year-old man with right sided weakness and incontinence.

Metastatic small cell carcinoma of lung, spinal intramedullary metastasis.

S

NH

BP-2010-02-203

A 20 year-old lady with a paraspinal mass.

Hodgkin's disease-mixed cellularity type.

S

NM

BP-2014-08-290

A 69 year-old woman with leg weakness and spinal mass.

Metastatic acinic cell carcinoma. Remote history of excised parotid well-differentiated acinic cell carcinoma.

S

NN

BP-2020-01-420

A 15 year-old boy with NF2 intracranial masses

Mixed Tumor with Schwannoma and Meningioma Components.

S

NN

BP-2019-05-403

A 55 year-old man with speech arrest.

Drop metastasis of an anaplastic oligodendroglioma, spinal cord.

S

NN

BP-2018-12-394

A 32 year-old woman with paravertabral mass.

Melanotic Schwannoma.

S

NN

BP-2017-03-352

A 53 year-old female with lumbar mass.

Malignant perineurioma (Malignant peripheral nerve sheath tumor with perineural differentiation).

S

NN

BP-2015-07-311

A 16 month-old male with head tilt, weakness, developmental delay and spinal mass.

Pilomyxoid Astrocytoma (WHO Grade II).

S

NN

BP-2015-05-308

11 year-old boy with sacral pain and lesion in lower spinal canal.

Malignant peripheral nerve sheath tumor (MPNST) / epithelioid and melanotic schwannoma.

S

NN

BP-2014-09-291

A 48 year-old woman with progressive hemisensory loss.

Extraventricular ganglioneurocytoma, WHO grade II (central neurcytoma with ganglionic component), cervical spine.

S

NN

BP-2014-02-276

A 46 year-old woman with leg numbness and spinal lesion.

Glioneuronal tumor with neuropil-like islands (GTNI), spinal cord.

S

NN

BP-2013-08-264

A 25 year-old woman with lumbago and intradural masses.

Myxopapillary ependymoma, WHO grade I, two foci in spinal cord.

S

NN

BP-2011-11-224

A 39 year-old man with syncope, nausea and vomiting.

 

Cerebellar oligodendroglioma with bone marrow metastasis.

S

NN

BP-2011-10-211

A 46 year-old man with lower extremity tingling.

Medulloblastoma, WHO Grade IV, consistent with late drop metastasis.

S

NN

BP-2008-06-165

A 55 year-old man with a paraspinal mass.

Malignant melanotic schwannoma.

S

NN

BP-2004-08-101

A man in his mid-60s with intermittent paresthesia of the abdomen and legs.

Pilocytic astrocytoma, spinal cord.

S

NN

BP-2004-04-097

A woman in her 50s with a cervical intra- and extraspinal mass lesion.

Malignant psammomatous melanotic schwannoma in a patient without signs of carney complex, spinal cord.

S

NN

BP-2000-10-055

A 47 year-old man with long-standing progressive tetraparesis.

Lymphoplasmacyte-rich meningioma, WHO grade I, multiple en plaque.

S

NN

BP-1998-04-025

A 30 year-old male with various sensory abnormalities.

Ganglioglioma, spinal cord.

S

NO

BP-2019-08-409

A 63 year-old man with cauda equina syndrome.

Spinal hibernoma (brown adipocytes in an otherwise unremarkable bone marrow).

S

NO

BP-2016-10-341

A 33 year-old man with paraparesis and lumbar mass.

Epstein-Barr virus-associated smooth muscle tumor, spinal cord.

S

NO

BP-2016-06-334

A 11 year-old boy with lumbar intradural mass.

Intradural, extramedullary granular cell tumor.

S

NO

BP-2016-06-333

A 60 year old man with lumbar mass.

Spinal paraganglioma (WHO grade I).

S

NO

BP-2016-05-332

A 64 year-old man with lumbar intradural mass.

Capillary hemangioma, spinal cord.

S

NO

BP-2015-07-312

A 24 year-old woman with acute back pain and spinal lesion.       

Ectopic adrenocortical adenoma of spinal canal, intradural, extramedullary.

S

NO

BP-2009-10-196

A 61 year-old woman with osteomalacia and a thoracic spine lesion.

Phosphaturic Mesenchymal Tumor, Mixed Connective Tissue Variant (PMT-MCT).

S

NO

BP-2005-03-108

A 15-year-old female with progressive myelopathy.

Ewing’s sarcoma (peripheral primitive neuroectodermal tumor), vertebral column.

S

NO

BP-2004-11-104

A 63 year-old woman with an intradural mass at the cauda equina.

Paraganglioma, gangliocytic variant.

S

NO

BP-2000-11-056

A 13 year-old girl with back pain and leg weakness.

Pigmented villonodular synovitis, vertebral column.

S

NO

BP-1998-01-022

A 43 year-old Caucasian male with progressive right lower extremity radicular pain.

Paraganglioma, filum terminale.

S

U

BP-2015-06-309

A 55 year-old Brazilian man with acute onset lower limb weakness and Guillain-Barré syndrome.

Leptomeningeal amelanotic melanomatosis and brain metastases from gastric melanoma.

S

U

BP-2012-01-227

A 55 year-old woman with leg pain.

Intradural schwannoma in schwannomatosis.

S

U

BP-2007-03-134

A 66 year-old male with spinal mass at autopsy.

Traumatic neuroma.

S

U

BP-2002-04-073

A 35 year-old healthy man with enlarging right parotid mass.

Castleman's disease, hyaline vascular type, vertebral column.

S

U

BP-2001-10-067

A 40 year-old Xhosa male with back pain and leg weakness.

Extramedullary hematopoiesis, dural based spinal cord.

S

U

BP-1998-03-024

A 42 year-old male with back pain, progressive right leg weakness and bilateral lower leg numbness.

Giant cell tumor of hyperparathyroidism (Brown tumor), thoracic spine.

S

V

BP-2016-05-331

Female in late 60’s with progressive paraplegia and sensory loss.

Foix-Alajouanine syndrome (Spinal dural arteriovenous fistula and related changes in spinal cord).

S

V

BP-2008-01-154

A 67 year-old male with progressive paraparesis.

Subacute necrotic myelitis/myelopathy (Foix-Alajouanine syndrome).

S

V

BP-2007-12-153

A 56 year-old male with left sided weakness.

Cerebral intraparenchymal myeloma.

S

V

BP-2001-05-062

A year-old female with dural mass encircling cervical spinal cord.

Granulomatous dural infiltrate with vasculitis, giant cells, and elevated c-ANCA titers; consistent with Wegener's granulomatosis involving dura of cervical spinal cord.

S

V

BP-2001-02-059

A year-old man with a history over 3 months of increasing dyspnea and malaise.

Spinal subarachnoid hemorrhage secondary to microscopic polyangiitis (Idiopathic late-onset cerebellar ataxia).