Case of the Month Published in Brain Pathology
International Society of Neuropathology
Listed by site and type with diagnosis.
Sorted by chronological order Sorted without diagnosis
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Site |
Type |
Number |
Clinical Information |
Diagnosis |
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B |
C |
A
59 year-old man with disseminated lung carcinoma and abnormal posterior
fossa. |
Dandy-Walker-Malformation. Mature midline posterior fossa
teratoma. Metastatic lung adenocarcinoma to the right cerebellar
hemisphere. |
|
|
B |
C |
Neonate
with occipital scalp defect. |
Primary
acalvaria, polymicrogyria, and partial destruction of brain stem and
cerebellum. |
|
|
B |
D |
A
63 year-old woman with dyspnoea, dysphagia and weakness. |
Multiple system atrophy. |
|
|
B |
D |
A
71 year-old woman with atypical Parkinson’s disease. |
Parkinson disease and hypoxic-ischemic encephalopathy. |
|
|
B |
D |
An
88 year-old woman with Parkinsonism. |
Post encephalitic Parkinsonism. |
|
|
B |
D |
A
12-year-old girl with seizures and dementia. |
Lafora body disease. |
|
|
B |
D |
A 70 year-old male with rigidity, decreased ocular
movements, and dementia. |
Progressive supranuclear palsy. |
|
|
B |
D |
A 24-year-old female with progressive lower extremity
dystonia, dysarthia, dysphagia and mental impairment. |
Hallervorden-Spatz disease (neurodegeneration with axonal
spheroids and iron depositions). |
|
|
B |
D |
A 13 year-old girl with progressive movement disorder. |
Huntington’s disease, juvenile onset. |
|
|
B |
F |
A
56 year-old woman with esophageal carcinoma, pancytopenia and visual
loss. |
Leukoencephalopathy, consistent with fludarabine
neurotoxicity. |
|
|
B |
F |
A
3 year-old boy with progressive hemiparesis and thalamic tumor. |
Gossypiboma (Textiloma) and residual pilocytic astrocytoma
WHO grade I. |
|
|
B |
F |
A
50 year-old
man with Burkitt lymphoma. |
Methotrexate-induced leukoencephalopathy |
|
|
B |
F |
A 62-year-old man with chronic pyothorax. |
Pyothorax-associated lymphoma. |
|
|
B |
F |
Two patients with putamen and white matter necrosis and
hemorrhage. |
Methanol intoxication.
|
|
|
B |
G |
A
13 year-old female with ADHD, cognitive delay and seizures. |
Niemann-Pick Disease, Type C. |
|
|
B |
G |
A 22
year-old woman with status epilepticus. |
Progressive
myoclonus epilepsy Lafora-type (LD, OMIM# 254780), confirmed also by
genetic testing, revealing a homozygous missense mutation (c.205C>G,
P69A) in the EPM2B (NHLRC1) gene. |
|
|
B |
G |
A
53 year-old
male with rapid cognitive decline. |
Kufs'
Disease (Adult Neuronal Ceroid Lipofuscinosis). |
|
|
B |
G |
A
12-year-old girl with seizures and dementia. |
Lafora body disease. |
|
|
B |
G |
A 70 year-old man with extrapyramidal symptoms, dementia and
hemosiderosis. |
Hereditary cerulopasmin deficiency with hemosiderosis.
|
|
|
B |
G |
A 48 year-old male with sudden onset of right sided
weakness. |
Posterior leukoencephalopathy; thrombotic microangiopathy
related to thrombotic thrombocytopenic purpura (TTP). |
|
|
B |
I |
A
70 year-old man presented with worsening cognition, speech impairment,
ataxia, and dysphagia, periodic episodes of brachial dystonia,
choreiform movements, and facial grimacing. |
Limbic encephalitis due to LGI1 antibodies. |
|
|
B |
I |
A
64 year-old man with visual disturbance and hippocampal swelling. |
Anti-Leucine Rich Glioma Inactivated 1 (LGI1) -
Autoimmune-mediated Limbic Encephalitis. |
|
|
B |
I |
A
77 year-old woman with tinnitus and mantle cell lymphoma. |
Atypical
gliosis with reactive changes, no evidence of mantle cell lymphoma. The
overall features are suggestive of progressive multifocal
leukoencephalopathy (PML). In situ
hybridization was positive for JC virus. |
|
|
B |
I |
A
37 year-old woman with cramps. |
Cerebral Schistosomiasis Caused by Schistosoma Mansoni. |
|
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B |
I |
A
55 year-old man with fever and headache. |
Neuroschistosomiasis, cerebellar acute schistosomal
encephalopathy infected by Schistosoma japonicum. |
|
|
B |
I |
A
42 year-old man with asthma, headache and nausea. |
Acute Hemorrhagic Leukoencephalitis (AHL) - Weston-Hurst's
disease. |
|
|
B |
I |
A
55 year-old man with headache and deep seated cerebral mass. |
Cerebral schistosomiasis. |
|
|
B |
I |
A
27 year-old woman with hemiparesis and cystic intracranial lesions. |
Multiple intracranial tuberculomas. |
|
|
B |
I |
A
32 year-old male with headache, visual loss and callosal lesion. |
Neurotuberculosis with parenchymatous acute arteritis and
cortical infarction. |
|
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B |
I |
A
63 year-old woman with apathy and drowsiness. |
Rheumatoid meningitis. |
|
|
B |
I |
A
52 year-old man with somnolence, irritability and memory disturbace. |
Cerebral Whipple's disease. |
|
|
B |
I |
A
59 year-old man with confusion, personality change and periventricular
lesions on MRI. |
Polymorphous post - transplant lymphoproliferative disorder,
EBV positive (PTLD). |
|
|
B |
I |
A
67 year-old man with long history of MS and cerebellar lesion. |
Progressive multifocal leukoencephalopathy (PML) with
superimposed immune reconstitution inflammatory syndrome (IRIS).
Quiescent multiple sclerosis plaques in multiple areas. |
|
|
B |
I |
A
20 year-old man with haedache, photophobia and reduced GCS. |
Tuberculous meningitis. |
|
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B |
I |
A
70 year-old male farmer with intermittent confusion. |
Necrotizing granulomatous encephalitis with
Mycobacterium caprae. |
|
|
B |
I |
A
20 year-old man with spastic tratrapareisis and hearing loss. |
Idiopathic hypertrophic pachymeningitis. |
|
|
B |
I |
A 58 year old HIV positive
Caucasian male presented with weight and appetite loss over 2 to 3
months. |
Progressive Multifocal
Leukoencephalopathy (PML) associated with Immune Reconstitution
Inflammatory Syndrome (IRIS). |
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|
B |
I |
A
54 year-old man with eye pain and visual loss. |
IgG4-related meningeal disease, previously classified as
idiopathic hypertrophic pachymeningitis (IHP). |
|
|
B |
I |
A
72 year-old woman with SLE and recent onset headache and ataxia. |
Progressive multifocal leukoencephalopathy (PML) in Systemic
Lupus Erythematosus (SLE). |
|
|
B |
I |
A
39 year-old male with fever and headaches. |
Toxoplasmosis of the hypothalamus, AIDS patient. |
|
|
B |
I |
A
30 year-old male with headache, hearing impairment and blackout. |
Schwannoma with exuberant inflammatory infiltrate and
intratumoral edema that may have caused the increase of mass effect and
sudden clinical deterioration. |
|
|
B |
I |
A
63 year-old woman with polycythaemia, vertigo, ataxia and weakness. |
Rosai Dorfman disease and multiple sclerosis. |
|
|
B |
I |
A
year-old man with sudden onset leg numbness. |
Neurosarcodosiss. |
|
|
B |
I |
A
49 year-old man with fever, altered mental state and enhancing brain
lesions on MRI. |
Disseminated Nocardiosis. |
|
|
B |
I |
A
47 year-old male with HIV infection and hemiplegia. |
Invasive aspergillosis of the CNS with secondary hemorrhagic
infarcts and subarachnoid hemorrhage in a patient with AIDS. |
|
|
B |
I |
A
2 year-old with anuria, diarrhoea and decreasing conscious level. |
Pneumocephalus due to Clostridium septicum in
association with hemolytic uremic syndrome. |
|
|
B |
I |
A
45-year-old male with left-sided hemi-hypesthesia. |
Tumefactive multiple sclerosis. |
|
|
B |
I |
A
76 year-old woman with paraplegia.
|
CNS spread of untreated acute myeloid leukemia associated
with acute demyelination. |
|
|
B |
I |
A 35
year-old HIV-positive woman with brain lesion. |
Acute
adenovirus encephalitis. |
|
|
B |
I |
A 7
year-old boy with acute encephalopathy. |
Influenza
associated acute necrotizing encephalopathy (ANE). |
|
|
B |
I |
A 31
year-old man with Balint’s syndrome. |
Subacute
sclerosing encephalitis (SSPE) and craniopharyngioma. |
|
|
B |
I |
An 80
year-old male with a ring-enhancing right basal ganglia lesion. |
Cerebral pheohypomycosis. |
|
|
B |
I |
A 55
year-old man with liver failure, delirium and seizures. |
Neurosarcoidosis. |
|
|
B |
I |
Leg
weakness after liver transplant. |
Coccidioidal granulomatous meningitis and abscesses. |
|
|
B |
I |
A 39-year-old man with new onset seizures. |
Intracerebral tuberculoma. |
|
|
B |
I |
A 49-year-old man with neuropsychiatric symptoms followed by
progressive cognitive decline. |
Sporadic Creutzfeldt-Jakob disease |
|
|
B |
I |
Young girl with headache and stiff neck. |
Granulomatous amebic meningoencephalitis caused by
Balamuthia mandrillaris.
|
|
|
B |
I |
A man in his 40s with headaches and dyspnea. |
Cryptococcal meningitis and
focal pneumonitis in a patient with pulmonary sarcoidosis. |
|
|
B |
I |
A 74-year-old man with history of gastric carcinoma
presented with partial-complex seizures. |
Neurocysticercosis. |
|
|
B |
I |
A 59-year-old woman with sudden onset of diplopia. |
Listerial rhombencephalitis. |
|
|
B |
I |
A 55-year-old diabetic male with progressive loss of
sensitivity. |
Toxoplasmosis. |
|
|
B |
I |
A 19 year-old male with febrile illness after jet ski
accident. |
Primary amebic meningoencephalitis (Naegleria fowleri). |
|
|
B |
I |
A 27 year-old female with epilepsy. |
Rasmussen’s encephalitis. |
|
|
B |
I |
A 35 year-old male with a left temporal lobe mass. |
Cerebral toxoplasmosis. |
|
|
B |
I |
A 21 year-old man with new-onset seizures and a temporal
lobe mass. |
Neurocysticercosis. |
|
|
B |
I |
A 36 year-old male with HIV infection and multiple cranial
neuritis. |
Cytomegalovirus (CMV) ventriculo-encephalitis,
polyradiculitis, and multiple cranial neuritis. |
|
|
B |
I |
A 26 year-old woman with new onset seizure. |
Progressive multifocal leukoencephalopathy (PML). |
|
|
B |
I |
A 60 year-old diabetic male with transient ischemic attack. |
Cryptococcal meningitis with vasculitis and cerebral
infarct. |
|
|
B |
I |
A 44 year-old woman with new brain lesion. |
Acute demyelinating lesion consistent with multiple
sclerosis. |
|
|
B |
NH |
An
83 year-old woman CML and meningioma. |
Myeloid sarcoma in CNS, as a blast transformation of chronic
myelomonocytic leukemia (CMML), subdural hematoma, meningothelial
meningioma (WHO Grade I). |
|
|
B |
NH |
A
66 year-old woman with cognitive decline and weakness. |
Lymphomatosis cerebri. |
|
|
B |
NH |
A
72 year-old woman with hearing loss and intraventricular mass. |
Primary CNS Lymphoplasmacytic Lymphoma. |
|
|
B |
NH |
A
68 year-old woman with MS and worsening skin lesions. |
CD8+ Cytotoxic T-Cell Lymphoma . |
|
|
B |
NH |
A
24 year-old man with seizure and scalp lesion. |
Spindle/sclerosing variant of follicular lymphoma. |
|
|
B |
NH |
A
60 year-old woman with hypertension and infarcts. |
Intravascular NK/T-cell lymphoma with associated multifocal
microinfarcts. |
|
|
B |
NH |
A
36 year-old female with facial sensory loss, headache, nausea and weight
loss. |
Multifocal intra-axial histiocytic sarcoma of the CNS,
primary versus metastatic. |
|
|
B |
NH |
A
22 year-old woman with retro-orbital pain. |
Langerhans cell histiocytosis, retro-orbital. |
|
|
B |
NH |
A
74 year-old woman with headache and weakness. |
Histiocytic Sarcoma, intra-axial. |
|
|
B |
NH |
A
30 year-old man with progressive visual field defect. |
Isolated extracranial-intracranial myeloid sarcoma,
monoblastic variant, cranial bone. |
|
|
B |
NH |
A
35 year-old man with painful forehead swelling and lytic skull lesion. |
Langerhans cell histiocytosis (LCH), cranium. |
|
|
B |
NH |
A
24 year-old woman with vertigo, vomiting and posterior fossa lesion. |
Natural killer (NK) cells lymphoblastic lymphoma/leukemia. |
|
|
B |
NH |
A
44 year-old obese, male smoker with involuntary movements and
intracranial lesion. |
Marginal zone B-cell lymphoma (MALT lymphoma), dural base. |
|
|
B |
NH |
A
77 year-old woman with headache and altered behavior. |
Marginal zone B-cell lymphoma (MALT lymphoma), dural base.
|
|
|
B |
NH |
A
78 year-old man with dysphagia, cranial nerve palsies and posterior
fossa mass. |
Atypical plasma cell neoplasm, extra-axial, posterior fossa
and jugular foramen. |
|
|
B |
NH |
A
78 year-old male with gait disturbance. |
Primary natural killer NK/T-cell lymphoma, nasal type, of
the central nervous system, intra-axial parietal mass. |
|
|
B |
NH |
A
29 year-old male with ring enhancing mass. |
Intracerebral Langerhans histiocytosis. |
|
|
B |
NH |
A
42 year-old woman with transient dizziness. |
Intravascular large B cell lymphoma. |
|
|
B |
NH |
A
76 year-old woman with paraplegia.
|
CNS spread of untreated acute myeloid leukemia associated
with acute demyelination. |
|
|
B |
NH |
A 61
year-old man with wide-based gait. |
Tumor-like
deposits of κ light chain surrounded by mature kappa chain-expressing
plasma cells. |
|
|
B |
NH |
A 76 year
old man with cognitive and neurological symptoms. |
T-cell lymphoma, cerebral. |
|
|
B |
NH |
A 46
year-old female with 5 month history of numbness in her toes. |
CNS
manifestation of multiple myeloma. |
|
|
B |
NH |
A 69
year-old man with left hemispheric necrotizing mass lesion. |
EBV-associated diffuse large B cell lymphoma and additional microglial
nodule encephalitis of the brainstem with associated severe hypoxic
injury of neurons. |
|
|
B |
NH |
A
51 year-old
female with double vision. |
Diffuse large B-cell lymphoma arising within a ganglioglioma
of the cerebellum. |
|
|
B |
NH |
A
year-old
woman with a clival mass. |
Langerhans cell histiocytosis, unifocal, clivus. |
|
|
B |
NH |
A 64 year-old woman with dementia and leukoencephalopathy. |
Lymphomatosis cerebri. |
|
|
B |
NH |
An 80-year-old female with neuropsychiatric changes. |
Angiotropic
(intravascular) lymphoma and cerebrovascular beta-amyloidosis. |
|
|
B |
NH |
A 43 year-old woman with a temporal mass. |
Granulocytic sarcoma, intracerebral. |
|
|
B |
NH |
A 62-year-old man with chronic pyothorax. |
Pyothorax-associated lymphoma. |
|
|
B |
NH |
A man in his late-40s with progressive dementia. |
Diffuse large B-cell lymphoma. |
|
|
B |
NH |
A 56-year-old woman with right frontal tumor of the dura. |
Marginal zone B-cell lymphoma (MALT lymphoma), dural based. |
|
|
B |
NH |
A 72 year-old woman with a pineal gland mass. |
High-grade non-Hodgkin’s B-cell lymphoma involving the
pineal and retroperitoneum. |
|
|
B |
NH |
A 29 year-old woman with a skull mass for two months |
Langerhans cell histiocytosis, cranium. |
|
|
B |
NH |
A 70-year-old female with seizures and progressive dementia. |
Intravascular lymphoma. |
|
|
B |
NM |
A
65 year-old man with sudden hemiplegia. |
Choriocarcinoma, likely metastatic. |
|
|
B |
NM |
A
39 year-old man with hematuria, headache and blurred vision. |
Metastatic chromophobe renal cell carcinoma in cerebellum. |
|
|
B |
NM |
A
40 year-old woman with recent onset headache and spinal masses. |
Metastasis of a gastrointestinal stromal tumor (GIST). |
|
|
B |
NM |
A
66 year-old man with previous prostate cancer and sphenoid wing tumor. |
Extra-osseous intracranial metastasis from prostatic
carcinoma. |
|
|
B |
NM |
A
59 year-old man with disseminated lung carcinoma and abnormal posterior
fossa. |
Dandy-Walker-Malformation. Mature midline posterior fossa
teratoma. Metastatic lung adenocarcinoma to the right cerebellar
hemisphere. |
|
|
B |
NM |
A
55 year-old Brazilian man with acute onset lower limb weakness and
Guillain-Barré syndrome. |
Leptomeningeal amelanotic melanomatosis and brain metastases
from gastric melanoma. |
|
|
B |
NM |
A
53 year-old woman with headache and vomiting. |
Intracranial tumor-to-tumor metastasis: Metastatic pulmonary
adenocarcinoma to a diffuse astrocytoma (WHO grade II). |
|
|
B |
NM |
A
76 year-old man with gait disturbance. |
Balloon cell melanoma, metastatic to cerebellum. |
|
|
B |
NM |
A
57 year-old woman with recurrent nausea and vomiting. |
Metastatic leiomyosarcoma, cerebellum. |
|
|
B |
NM |
A
Posterior fossa lesion 45 years after ocular trauma. |
Epithelioid and spindle cell conjunctival melanoma and
metastatic epithelioid and spindle cell conjunctival melanoma. |
|
|
B |
NM |
A
41 year-old woman with von Hippel-Lindau and a cerebellar Lesion |
Clear cell renal cell carcinoma metastatic to illary
hemangioblastosma in the setting of von Hippel- Lindau disease. |
|
|
B |
NM |
A 72 year
old man with new seizure while dancing. |
Metastatic
clear-cell type of renal carcinoma in a meningothelial meningioma. |
|
|
B |
NM |
A
70 year-old
man with enlarged pineal gland. |
Solitary
pineal metastasis of prostate adenocarcinoma with changes of secondary
acute hydrocephalus. |
|
|
B |
NM |
A year-old man with a history of Hodgkin’s disease. |
Metastatic Hodgkin’s disease. |
|
|
B |
NN |
A
8 year-old girl with headache and fourth ventricular mass |
First, second, and fourth resection: Posterior fossa
Ependymoma (WHO grade III; Methylation subgroup A); Malignant glioma,
corresponding to glioblastoma (WHO grade IV), most likely radiation
induced |
|
|
B |
NN |
A
4 year-old girl with hemiparesis and ataxia. |
Diffuse glioma, H3K27M-mutant, thalamus. |
|
|
B |
NN |
A
58 year-old man with headache and temporal parietal mass. |
Anaplastic pilomyxoid astrocytoma. |
|
|
B |
NN |
A
39 year-old man with seizure and visual impairment. |
Diffuse, Grade II astrocytoma, IDH-mutant, 1p/19q-intact,
anaplastic, Grade III oligoastrocytoma (OA) with a dual genotype. |
|
|
B |
NN |
A
8 year-old girl with headache and ‘heartbeat’ eyelid movements and loss
of consciousness. |
Angiocentric Glioma. |
|
|
B |
NN |
A
25 year-old man with gait disturbance. |
Anaplastic ependymoma (WHO Grade III) with neuropil-like
islands. |
|
|
B |
NN |
A
82 year-old man with 3 months of cognitive decline. |
Meningioma with iron-positive macrophages
(pseudo-pigmentation). |
|
|
B |
NN |
A
44 year-old woman with 2 weeks of headache. |
Clear cell ependymoma, WHO grade II. |
|
|
B |
NN |
A
77 year-old man with tremor and gait problems. |
Diffuse glioma exhibiting growth and invasion pattern of
gliomatosis cerebri. |
|
|
B |
NN |
A
9 year-old girl with hemiplegia, headache and vomiting. |
Anaplastic astrocytoma of the pons/ WHO Grade III (DIPG)
(H3K27M mutation was not checked) |
|
|
B |
NN |
A
37 year-old woman with blurred vision and hemianopia. |
Atypical Teratoid/Rhabdoid Tumor. |
|
|
B |
NN |
A
8 year-old girl with headaches, vomiting and deep seated mass. |
Small Cell Astrocytoma (H3K27M mutant, it should be now
classified as diffuse midline glioma with H3K27M mutation), mass in
basal ganglia and medial temporal lobe. |
|
|
B |
NN |
A
19 year-old male with narcolepsy and dural masses. |
Disseminated oligodendroglial-like leptomeningeal tumor with
malignant (anaplastic) transformation. |
|
|
B |
NN |
A
55 year-old woman headaches and leptomeningeal pigmentation |
Diffuse leptomeningeal melanocytoma with no BRAF mutation. |
|
|
B |
NN |
A
32 year-old man with headaches and vascular lesion in temporal region. |
Arteriovenous malformation associated with anaplastic
astrocytoma. |
|
|
B |
NN |
A
59 year-old woman with headache and retrosellar mass. |
Atypical extra-ventricular ganglioneurocytoma. |
|
|
B |
NN |
A
14 year-old boy with headache and seizure. |
Atypical teratoid rhabdoid tumor. |
|
|
B |
NN |
A
34 year-old man with headaches, confusion and hemiparesis. |
Glioblastoma with primitive neuroectodermal (PNET) features
and metastasis of the PNET component, frontal-temporal-parietal mass. |
|
|
B |
NN |
A
74 year-old man with hearing loss, imbalance and hand numbness. |
Schwannoma, jugular foramen. |
|
|
B |
NN |
41 year-old male with long history of seizures and
subcortical parietal lesion. |
Angiocentric glioma, WHO grade I. |
|
|
B |
NN |
A
11 year-old boy who sustained head injury after episode of vertigo and
visual disturbance. |
Anaplastic ependymoma (WHO grade III) with granular cell
features. |
|
|
B |
NN |
A
64 year-old woman admitted with fatigue, headache, and weight loss. |
Primary diffuse leptomeningeal gliomatosis (PDLG) (WHO grade
III). |
|
|
B |
NN |
A
26 year-old woman with visual disturbance prepontine mass. |
Medulloblastoma, desmin positive, with drop metastases. |
|
|
B |
NN |
Two cases of intraventricular haemorrhage. |
Central neurocytoma, WHO grade II, complicated by
hemorrhage. |
|
|
B |
NN |
A
6 year-old girl with headache, vomiting and syncope and large parietal
mass. |
Malignant peripheral nerve sheath tumor, parietal
extra-axial mass. |
|
|
B |
NN |
A
56 year-old man with congenital heart disease and ring enhancing
cerebral lesions. |
Granular cell astrocytoma. |
|
|
B |
NN |
A
72 year-old woman with back pain and spinal mass. |
Intradural melanocytoma, spinal cord. |
|
|
B |
NN |
A
49 year-old woman with ovarian tumor and pineal mass. |
Papillary tumor of the pineal region, WHO grade II-III. |
|
|
B |
NN |
A
26 year-old man with memory loss and lethargy. |
Chordoid glioma of the third ventricle, WHO grade II, mass
in third ventricle and lateral ventricle, midline. |
|
|
B |
NN |
A
30 year-old male with headaches. |
Anaplastic central neurocytoma, septum pellucidum and
bilateral lateral ventricles. |
|
|
B |
NN |
An
8 year-old male with headaches and vomiting. |
Glioblastoma, WHO grade IV, with extensive neuronal
differentiation. |
|
|
B |
NN |
A
29 year-old male with seizures. |
Anaplastic oligodendroglioma, WHO grade III. |
|
|
B |
NN |
A
24 year-old female with MS and intracranial mass. |
Hybrid peripheral nerve sheath tumor, with
schwannoma/perineurioma components. |
|
|
B |
NN |
A
40 year-old male with vertigo and headaches. |
Combined tanycytic ependymoma and subependymoma, (WHO grade
II). |
|
|
B |
NN |
A
30 year-old male with headache, hearing impairment and blackout. |
Schwannoma with exuberant inflammatory infiltrate and
intratumoral edema that may have caused the increase of mass effect and
sudden clinical deterioration. |
|
|
B |
NN |
A
26 year-old male with difficulty in walking, diplopia and unilateral
shaking. |
Medulloblastoma, WHO Grade IV, with divergent
differentiation including myoblastic, glial, osteoblastic and
chondroblastic differentiation. |
|
|
B |
NN |
A
14 year-old girl with sciatica and ataxia. |
Multicentric pleomorphic xanthoastrocytoma (PXA; WHO grade
II) with leptomeningeal dissemination. |
|
|
B |
NN |
A
23 year-old man with seizures and cystic lesion. |
Pigmented (melanin producing) desmoplastic ganglioglioma. |
|
|
B |
NN |
A 4 month-old with vomiting, seizures and large cerebral mass. |
Cystic atypical choroid plexus papilloma, WHO grade II. |
|
|
B |
NN |
A
45 year-old man with pineal region tumor.
|
Papillary tumor of the pineal region (2007 WHO
Classification assigns a Grade II to III). |
|
|
B |
NN |
A
71 year-old woman with headache and proptosis. |
Primary extradural meningioma, intraosseous type, WHO Grade
I. |
|
|
B |
NN |
A
58 year-old man with phacomatosis, tinnitus, deafness and headaches. |
Schwannoma grade I WHO of the jugular foramen associated
with leptomeningeal blue nevus. |
|
|
B |
NN |
A
2 year-old boy with imbalance and strabismus. |
Medulloblastoma with rhabdomyoblastic differentiation
("medullomyoblastoma"). |
|
|
B |
NN |
A
16 month-old girl with fever, hypoxia and seizures. |
Congenital intraventricular atypical meningioma and
neurofibromatosis 2 (NF2). |
|
|
B |
NN |
A
3 year-old girl with altered mental status, gait difficulty and
vomiting. |
Embryonal tumor with abundant neuropil and true rosettes
(ETANTR). |
|
|
B |
NN |
A
17 year-old girl with headache and complex partial seizure. |
Extra-axial anaplastic ependymoma. |
|
|
B |
NN |
A
35 year-old man with falcine tumor. |
Primary intracranial solitary leptomeningeal astrocytoma
(WHO grade III). |
|
|
B |
NN |
A
81 year-old male with confusion and weakness.
|
Glioblastoma (WHO grade IV) with primitive neuroectodermal
tumor (PNET)-like component. |
|
|
B |
NN |
A
12 year-old boy with multiple brain masses. |
#1
-
Anaplastic medulloblastoma, #2
- Low-grade lipoastrocytoma,
#3 - Pilocytic
astrocytoma with radiation induced modification. |
|
|
B |
NN |
A 25
year-old woman with a mass in the hippocampus. |
Angiocentric glioma in the hippocampus. |
|
|
B |
NN |
A 6
year-old with an extra-axial mass. |
Atypical
meningioma associated with reactive hyperplasia and colonization of
meningeal melanocytes. |
|
|
B |
NN |
A 22
year-old man with intracranial hypertension. |
Primary
diffuse leptomeningeal primitive neuroectodermal tumor (PDL PNET). |
|
|
B |
NN |
A 6
year-old girl with hydrocephalus. |
Pediatric
tectal glioma with focal anaplasia. |
|
|
B |
NN |
A 15
year-old boy with a posterior fossa tumor. |
Pigmented pleomorphic xathoastrocytoma. |
|
|
B |
NN |
A 2
year-old girl with a posterior fossa tumor. |
Embryonal
Tumor with Abundant Neuropil and True Rosettes (ETANTR). |
|
|
B |
NN |
A 12
year-old boy with a posterior fossa tumor. |
Glioblastoma multiforme, WHO grade IV. |
|
|
B |
NN |
A 33
year-old Chinese woman with a left frontal lobe tumor. |
Astroblastoma. |
|
|
B |
NN |
A 32
year-old man with a fourth ventricular mass. |
Intraventricular astrocytoma with extensive lipidization
(lipoastrocytoma). |
|
|
B |
NN |
A 16
year-old male with cerebellar mass. |
Cerebellar
pleomorphic xanthoastrocytoma. |
|
|
B |
NN |
A 28
year-old man with headache and aphasic speech and visual disturbances. |
Pleomorphic
xanthoastrocytoma with anaplastic features (WHO grade III) rapidly
progressing towards pleomorphic xanthoastrosarcoma (WHO grade IV). |
|
|
B |
NN |
A 50
year-old woman with pigmented tumor of the 4th ventricle. |
Primary CNS
melanocytic tumor of intermediate type progressing to metastatic
melanoma. |
|
|
B |
NN |
Recurrent
cerebellar lesion in a young boy. |
Cerebellar neurocytoma. |
|
|
B |
NN |
A
2 year-old
girls with right leg weakness. |
Glioblastoma multiforme, WHO grade IV. |
|
|
B |
NN |
A
44 year-old
man with abnormal gait. |
Choroid plexus papilloma, oncocytic variant. |
|
|
B |
NN |
A
72 year-old
woman with right frontal mass. |
Plasma cell
predominant lymphoplasmacytic-rich meningioma, grade I (WHO), with
crystalline inclusions. |
|
|
B |
NN |
A
21 month
old child with acute spastic paraparesis |
Stroma poor ganglioneuroblastoma of sympathetic ganglion. |
|
|
B |
NN |
A
49 year-old
female with history of head trauma. |
Infiltrating meningioma. |
|
|
B |
NN |
A
43 year-old
Chinese man with retro-orbital mass. |
Cellular schwannoma, orbit. |
|
|
B |
NN |
A
15 year-old
girl with cystic tumor. |
Pleomorphic xanthoastrocytoma with anaplastic features.
|
|
|
B |
NN |
A
40 year-old
male with history of brain tumor 10 years ago. |
1992 diagnosis: astrocytoma, WHO grade II, BP-2002-
diagnosis: primitive neuroectodermal tumor (PNET), WHO grade IV. |
|
|
B |
NN |
A
30-year-old
man with tuberous sclerosis. |
Subependymoma giant cell astrocytoma with malignant
phenotype and axial spread. |
|
|
B |
NN |
A
35-year-old
woman with dural-based mass. |
Pleomorphic xanthoastrocytoma. |
|
|
B |
NN |
A
76 year-old
woman with recent bladder cancer and new brain lesion. |
Diffuse high-grade glioma. |
|
|
B |
NN |
A 37 year-old pregnant woman with new onset seizures. |
Myxoid meningioma. |
|
|
B |
NN |
A 37-year-old male with headache. |
Low-grade astroblastoma, cerebellum. |
|
|
B |
NN |
A 42 year-old man with a densely vascular spinal mass. |
De novo malignant ganglioglioma of the spinal cord with unusually
prominent dysplastic vessels (“malignant angio-ganglioma”). |
|
|
B |
NN |
A 57-year-old female with a benign tumor in the ethmoid
sinus. |
Olfactory neurocytoma. |
|
|
B |
NN |
A 4-year-old girl with mass in the frontotemporal bone. |
Melanotic neuroectodermal tumor of infancy. |
|
|
B |
NN |
A 21-year-old female with a cystic brain lesion. |
Gangliocytoma, intracerebral. |
|
|
B |
NN |
A 19-year-old male with generalized seizures,
unconsciousness and a deviation of gaze. |
Light chain deposition disease of the brain following
low-grade lymphoma. |
|
|
B |
NN |
A 35-year-old woman with progressive bilateral leg weakness. |
Intermediate grade melanocytoma, spinal cord. |
|
|
B |
NN |
A 45 year-old male with symptomatic mass in the frontal
lobe. |
Oligodendroglioma, WHO grade II with neurocytic
differentiation. |
|
|
B |
NN |
A 21-year-old female with a third ventricular tumor. |
Intraventricular schwannoma, WHO grade I. |
|
|
B |
NN |
Woman aged 24 years with fourth ventricular mass. |
Giant cell ependymoma. |
|
|
B |
NN |
A 10-month-old boy with a large pineal tumor. |
Pineal anlage tumor without immature components. |
|
|
B |
NN |
A 7-year-old boy with midline cerebella mass. |
Primitive neuroectodermal tumor (PNET) showing multilineal
differentiation. |
|
|
B |
NN |
A 1 year-old girl with an aggressive skull tumor. |
Malignant melanotic neuroectodermal tumor of infancy
involving the brain, cranial bone and scalp. |
|
|
B |
NN |
A male in his late 60s with recurrent extracerebral tumor. |
Recurrent pure rhabdoid
meningioma evolving from a transitional meningioma with rhabdoid-like
tumor areas. |
|
|
B |
NN |
A 24-year-old woman with a one-year history of bifrontal
headaches. |
Extraventricular neurocytoma. |
|
|
B |
NN |
A 70-year-old woman with a recurrent meningeal mass. |
Recurrent meningioma with rhabdomyosarcomatous
differentiation. |
|
|
B |
NN |
Neonatal female with congenital brain tumor. |
Gemistocytic astrocytoma, congenital. |
|
|
B |
NN |
A 79 year-old woman with right frontal lobe mass. |
Gliosarcoma. |
|
|
B |
NN |
A 33-year-old male with a long history of epilepsy. |
Meningioma and meningioangiomatosis. |
|
|
B |
NN |
A 24 year-old female with a parietal occipital tumor. |
Papillary glial neuronal tumor |
|
|
B |
NN |
A 21 year-old male with cystic intracerebral tumor. |
Schwannoma, intracerebral. |
|
|
B |
NN |
A 57 year-old male with leptomeningeal and liver tumors. |
Metastatizing, melanocytic leptomeningeal tumor with
histomorphological characteristics of a melanocytoma. |
|
|
B |
NN |
A 28 year-old woman with neck and back pain. |
Plexiform neurofibroma, facial nerve. |
|
|
B |
NN |
A 51 year-old
man with seizures since childhood. |
Ganglioglioma with neurofibrillary tangles. |
|
|
B |
NN |
A year-old woman with gait disorders. |
Meningothelial meningioma with lipomatous and rhabdoid
differentiation. |
|
|
B |
NN |
A year-old female with a cerebellar mass. |
Lhermitte-Duclos disease (dysplastic gangliocytoma of the
cerebellum). |
|
|
B |
NN |
A 16 year-old boy with 2-week history of progressive
lethargy. |
Desmoplasmic infantile ganglioglioma, WHO grade I. |
|
|
B |
NN |
A 43 year-old male with generalized epileptic seizures. |
Lymphoplasmacyte-rich meningioma, WHO grade I. |
|
|
B |
NN |
A 5 month-old boy with occipital bone mass. |
Melanotic neuroectodermal tumour of infancy. |
|
|
B |
NN |
A 12-year-old boy with recent onset seizures. |
Extraventricular atypical neurocytic neoplasm ("cystic
ganglioneurocytoma"). |
|
|
B |
NN |
A 22-year-old female with intraventricular mass. |
Choroid plexus carcinoma. |
|
|
B |
NN |
A 16-year-old male with history of low-grade astrocytoma. |
Pilocytic astrocytoma, WHO grade I, with widespread
dissemination in the CNS. |
|
|
B |
NN |
A29 week-gestational age newborn with echogenic mass in
third ventricle. |
Primitive neuroectodermal tumor (PNET), congenital. |
|
|
B |
NN |
A 61 year-old male with brain tumor and oral, lung, and
palpebral masses. |
Gliosarcoma with selective extraneural sarcoma metastases. |
|
|
B |
NN |
An 18 year-old male with large cystic orbital tumor. |
Pilocytic astrocytoma with cystic degeneration and evidence
of old and fresh hemorrhage, orbit. |
|
|
B |
NN |
A 45 year-old man with headache, ataxia, and impairment of
the state of balance. |
Pineocytoma with neuronal differentiation, WHO grade II. |
|
|
B |
NN |
A 42 year-old man with left facial weakness. |
Malignant epithelioid schwannoma, trigeminofacial nerve. |
|
|
B |
NN |
A 31 year-old woman with seizures, fatigue and attention
deficits. |
Dysembryoplastic neuroepithelial tumor (DNET). |
|
|
B |
NN |
A 4 year-old girl with ring chromosome 22 and brain tumor. |
Atypical teratoid/rhabdoid tumor with ring chromosome 22. |
|
|
B |
NN |
A 9 year-old girl with nausea, vomiting and hydrocephalus. |
Anaplastic ependymoma, WHO grade III. |
|
|
B |
NN |
A 22 month-old girl with a cervicomedullary mass. |
Pilocytic astrocytoma with focal palisading features of
formerly “primitive polar spongioblastoma” |
|
|
B |
NN |
An 11 year-old girl with frontal lobe tumor. |
Central neurocytoma. |
|
|
B |
NN |
A 4 year-old girl with precocious puberty. |
Hypothalamic hamartoma. |
|
|
B |
NN |
A 9 month-old infant with hydrocephalus. |
Pigmented choroid plexus papilloma. |
|
|
B |
NO |
A
21 month-old male with cerebellar mass. |
Germinoma. |
|
|
B |
NO |
A
55 year-old man with speech and behavioral change. |
High-grade intracerebral myxofibrosarcoma, intra-axial. |
|
|
B |
NO |
A
41 year-old woman with headache and dizziness. |
Meningeal solitary fibrous tumor/hemangiopericytoma with
ectopic salivary gland tissue. |
|
|
B |
NO |
A
43 year-old man with scalp swelling. |
Primary intracranial leiomyosarcoma arising from the dura. |
|
|
B |
NO |
A
50 year-old man with diabetes, hypertension and hypothalamic ,mass. |
Hemangioblastoma of the hypothalamus. |
|
|
B |
NO |
A
36 year-old woman with ptosis.
|
Epithelial-Myoepithelial Cell Carcinoma (EMCC) |
|
|
B |
NO |
A
15 month-old boy with cerebellar mass. |
Yolk sac tumor, cerebellum. |
|
|
B |
NO |
A
63 year-old woman with mass on forehead. |
Low-grade central osteosarcoma. |
|
|
B |
NO |
A
74 year-old woman with head injury and intracranial lesion. |
Intracranial low-grade fibromyxoid sarcoma. |
|
|
B |
NO |
A
72 year-old man with gait disturbance, headache and pineal mass. |
Solitary fibrous tumor (SFT) of the pineal region. |
|
|
B |
NO |
A
50 year-old man with presumed meningiomas. |
Angiomyxofibroma, dural based intra-cerebral. |
|
|
B |
NO |
A
19 year-old male with blurred vision, headache and large lobulated
occipital mass. |
Intracerebral Chondroma. |
|
|
B |
NO |
A
36 year-old man with multiple meningiomas and nasal mass. |
Olfactory neuroepithelioma. |
|
|
B |
NO |
A
3 year-old boy with progressive hemiparesis and thalamic tumor. |
Gossypiboma (Textiloma) and residual pilocytic astrocytoma
WHO grade I. |
|
|
B |
NO |
A
65 year-old woman with facial pain and CP angle tumor. |
Epidermoid Cyst with Malignant Transformation to Squamous
Cell Carcinoma. |
|
|
B |
NO |
A
49 year-old woman with dysphagia and foramen magnum lesion. |
Myopericytoma, cranial base. |
|
|
B |
NO |
A
12 year-old boy with progressive hemiparesis. |
Germinoma, thalamus and cerebral peduncle. |
|
|
B |
NO |
A
2 year-old girl with large parieto-occiptal mass. |
Malignant myoepithelioma with extensive leptomeningeal
spread to the cervical, thoracic and lumbar spine. |
|
|
B |
NO |
A
19 year-old man with headache, neck stiffness and hemiparesis. |
Disseminated anaplastic hemangiopericytoma WHO grade III /
solitary fibrous tumor, cellular type. |
|
|
B |
NO |
A
40 year-old female with headache, vomiting and superficial lesions in
brain. |
Primary leptomeningeal sarcomatosis. |
|
|
B |
NO |
A
43 year-old woman with 6 months of nausea and vomiting causing
significant weight loss, followed by ataxia and nystagmus. |
Histiocytic sarcoma, multifocal, intra-axial and
periventricular |
|
|
B |
NO |
A
59 year-old woman with nausea, vomiting and cerebellopontine area mass. |
Malignant Triton tumor (High-grade malignant peripheral
nerve sheath tumor with rhabdomyosarcomatous differentiation),
cerebellopontine angle. |
|
|
B |
NO |
A
37 year-old woman with headache, weakness and ventricular mass. |
Intracranial solitary fibrous tumor with atypical histologic
features (hemangiopericytoma) and distant bone metastases. |
|
|
B |
NO |
A
40 year-old woman with sudden onset headache. |
Lipomatous hemangiopericytoma (Fat forming solitary fibrous
tumor) associated with oncogenic osteomalacia, mass in cranial base. |
|
|
B |
NO |
A
42 year-old man with new onset seizures and well circumscribed temporal
lobe mass. |
Benign fibrous tumor (fibroma), extra-axial parietal. |
|
|
B |
NO |
A
73 year-old male with progressive tetraparesis. |
Giant cell-rich solitary fibrous tumor, extra-axial dorsal
lower medullar mass. |
|
|
B |
NO |
A
59 year-old female with neck and arm pain. |
Inflammatory myofibroblastic tumor, extra-axial posterior
fossa. |
|
|
B |
NO |
A
68 year-old male with hearing loss. |
Fetal type myxoid rhabdomyoma of the vestibular nerve. |
|
|
B |
NO |
A
47 year-old woman with headache, visual and swallowing difficulties. |
Chondroma of cerebellopontine angle. |
|
|
B |
NO |
A
64 year-old woman with anosmia. |
Sinonasal undifferentiated carcinoma. |
|
|
B |
NO |
A
18 year-old woman motor cyclist who crashed with a subdural mass. |
Chondrona of dural convexity. |
|
|
B |
NO |
A
48 year-old man with vascular disease, vertigo, tinnitus, diplopia and
ataxia. |
Metastatic hemangioblastoma (disseminated
hemangioblastomatosis). |
|
|
B |
NO |
A
47 year-old man with lower extremity weakness. |
Low- grade myofibroblastic sarcoma, right frontal lobe. |
|
|
B |
NO |
A
56 year-old woman with headache. |
Chondromyxoid fibroma, sphenoid bone. |
|
|
B |
NO |
A 58 year
old woman with a corpus callosum nodule at autopsy. |
Lipoma of
the Corpus Callosum. |
|
|
B |
NO |
A 47
year-old male with a cerebellopontine angle tumor. |
Angiolipomatous hamartoma of the cochlear nerve. |
|
|
B |
NO |
A 64
year-old man with atypical cerebral lesions. |
Angiosarcoma, cerebral. |
|
|
B |
NO |
A 5
year-old male with interhemispheric frontal mass. |
Encephalic lipoma (tubulonodular type) with
neuroglial component associated with partial agenesis of the corpus
callosum. |
|
|
B |
NO |
A 5
year-old boy with a clival mass. |
Epithelioid sarcoma. |
|
|
B |
NO |
A 59
year-old male with sellar mass. |
Pituitary
gonadotroph adenoma with adamantinomatous craniopharyngioma. |
|
|
B |
NO |
A
23 year-old
Hispanic male with new onset seizures. |
Masson's
tumor (papillary endothelial hyperplasia), intracerebral. |
|
|
B |
NO |
A
40 year-old
woman with a progressive periventricular white matter lesion. |
Diffusely infiltrating germinoma. |
|
|
B |
NO |
A
57-year-old man with a dural-based parietal lobe tumor. |
Supratentorial hemangioblastoma. |
|
|
B |
NO |
A
27 year-old
female with cranial nerve dysfunction. |
Chondroblastoma, petrous portion of the temporal bone. |
|
|
B |
NO |
A 44-year-old man with a 2-year history of epistaxis. |
Paraganglioma, nasopharyngeal. |
|
|
B |
NO |
A 47-year-old-woman with a 7-year-history of osteomalacia
and hypophosphatemia. |
Phosphaturic mesenchymal tumor (mixed connective tissue
variant) of the cavernous sinus. |
|
|
B |
NO |
A 53-year-old male with new onset seizures. |
Osteochondroma, intra-cranial. |
|
|
B |
NO |
A 66 year-old female with a one-year history of progressive
left proptosis. |
Solitary fibrous tumor, orbit. |
|
|
B |
NO |
A year-old female with progressive confusion lethargy and
headaches. |
Malignant solitary fibrous tumor, intra-cranial dural based. |
|
|
B |
NO |
A 68 year-old woman with a history of progressive hearing
loss. |
Endolymphatic sac tumor clinically mimicking jugular
paraganglioma. |
|
|
B |
NO |
A 44-year-old man with a bleeding intracerebral tumor. |
Primary embryonal rhabdomyosarcoma of the brain,
intra-axial. |
|
|
B |
NO |
A 26-year-old male with a history of AIDS. |
Leiomyoma associated with EBV, skull base. |
|
|
B |
NO |
A 41 year-old female with a dura based occipital mass |
Solitary fibrous tumor, dural based. |
|
|
B |
U |
A
33 year-old woman with head and neck pain for 5 years. |
Calcifying pseudoneoplasm of the neuraxis (CAPNON),
cerebellopontine angle. |
|
|
B |
U |
A
39 year-old woman with fever and headache for 9 months. |
Chordoid meningioma with Castleman Syndrome. |
|
|
B |
U |
A
72 year-old woman with progressive confusion and dural masses. |
Erdheim-Chester Disease |
|
|
B |
U |
A
43 year-old woman with headache and subarachnoid hemorrhage. |
CNS Rosai-Dorfman disease with extensive meningeal and
parenchymal involvement, and thrombosis in the venous sinuses followed
by secondary multiple hemorrhagic infarcts. |
|
|
B |
U |
A
36 year-old man with solvent exposure, headache and fever. |
Inflammatory Amyloid Angiopathy and leptomeningeal
amyloidosis with inflammation. |
|
|
B |
U |
A
44 year-old woman with familial Mediterranean fever and cardiac arrest. |
Systemic amyloid A (AA) amyloidosis with amyloid deposition
in the choroid plexus and pituitary gland. |
|
|
B |
U |
A
68 year-old woman with sudden onset fluent aphasia. |
Rosai-Dorfman meningeal disease with IgG4-related disease
histological features. |
|
|
B |
U |
A
11 year-old male with headache, cranial nerve palsy and spinal meningeal
lesion on MRI. |
Leptomeningeal melanocytosis in the context of
neurocutaneous melanosis with NRAS mutation (Q61K). |
|
|
B |
U |
A
61 year-old male with prolactinoma treated with cabergoline. |
Nodular amyloidoma of the pituitary gland/skull base. |
|
|
B |
U |
A
64 year-old man with seizure and extraaxial mass. |
Dural based extranodal Rosai Dorfman disease. |
|
|
B |
U |
A
71 year-old man with headache, visual disturbance and agraphia |
Amyloidoma, cerebral. |
|
|
B |
U |
A
67 year-old woman with back pain and intramedullary mass. |
Tophaceous pseudogout, intradural and intramedullary mass. |
|
|
B |
U |
A
31 year-old woman with neck pain and clival mass. |
Calcifying pseudoneoplasm of the neural axis (CAPNON). |
|
|
B |
U |
A
63 year-old woman with polycythaemia, vertigo, ataxia and weakness. |
Rosai Dorfman disease and multiple sclerosis. |
|
|
B |
U |
3 A
2 year-old male with fever and diahorrea. Previous subarachnoid
haemorrahage followed by cognitive problems. |
Cerebral multifocal intracerebral schwannosis. |
|
|
B |
U |
A
3 year-old boy with drug-resistant seizures, naevi and lesion in uncus. |
Neurocutaneous melanosis. |
|
|
B |
U |
A
38 year-old woman with diabetes insipidus, headache and hemiplegia. |
Intracranial xanthogranuloma. |
|
|
B |
U |
A
37 year-old woman with deteriorating vision. |
Multiple intracranial meningeal extramedullary
hematopoiesis. |
|
|
B |
U |
A 6
year-old with an extra-axial mass. |
Atypical
meningioma associated with reactive hyperplasia and colonization of
meningeal melanocytes. |
|
|
B |
U |
A 60
year-old female with extra-axial frontal mass. |
Erdheim-Chester Disease. |
|
|
B |
U |
A 51
year-old man with sudden unexpected death. |
Acute
subarachnoid and intraventricular hemorrhage secondary to acute
hemorrhage within a choroid plexus xanthogranuloma. |
|
|
B |
U |
An
8 year-old
child with lesion in the lentiform nucleus. |
Rosai-Dorfman disease, intracerebral. |
|
|
B |
U |
An 80-year-old female with neuropsychiatric changes. |
Angiotropic
(intravascular) lymphoma and cerebrovascular beta-amyloidosis. |
|
|
B |
U |
A 19-year-old male with generalized seizures,
unconsciousness and a deviation of gaze. |
Light chain deposition disease of the brain following
low-grade lymphoma. |
|
|
B |
U |
Newborn with intracranial mass. |
Chronic intracerebral hemorrhage of unknown etiology with
reactive changes of the surrounding brain tissue and focal
extramedullary erythropoiesis. |
|
|
B |
U |
A 33-year-old male with a long history of epilepsy. |
Meningioma and meningioangiomatosis. |
|
|
B |
U |
A 57-year-old woman with slurred speech. |
Rosai-Dorfman disease, leptomeningeal. |
|
|
B |
U |
A 38 year-old man and 69-year-old woman with dural based
masses. |
Destombes-Rosai-Dorfman Disease,
dural based. |
|
|
B |
U |
A year-old man with a temporal bone mass. |
Giant cholesterol granuloma of the petrous portion of the
temporal bone with a small component of coexistent cholesteatoma. |
|
|
B |
U |
A 15 year-old girl with parietal lobe lesion. |
Solitary juvenile xanthogranuloma, solitary brain
involvement without skin involvement.
|
|
|
B |
U |
A 32 year-old man with mental status changes and a severe
occipital headache. |
Acute hemorrhagic leukoencephalopathy. |
|
|
B |
U |
A 7 year-old girl with seizures. |
Meningioangiomatosis. |
|
|
B |
V |
A
32 year-old male with headache, visual loss and callosal lesion. |
Neurotuberculosis with parenchymatous acute arteritis and
cortical infarction. |
|
|
B |
V |
A
78 year-old woman who became unrousable following a hip
hemiarthroplasty. |
Fat embolism leading to cerebral edema with tentorial and
tonsillar herniation. |
|
|
B |
V |
A
36 year-old male with pulsatile crainal mass developing after head
injury. |
Sinus pericranii - the final
diagnosis was based on the clinical, radiological and histopathological
findings. |
|
|
B |
V |
A
32 year-old man with headaches and vascular lesion in temporal region. |
Arteriovenous malformation associated with anaplastic
astrocytoma. |
|
|
B |
V |
A
29 year-old female with confusion and ataxia. |
Moyamoya disease. |
|
|
B |
V |
A
71 year-old woman with atypical Parkinson’s disease. |
Parkinson disease and hypoxic-ischemic encephalopathy. |
|
|
B |
V |
A
11 year-old girl with scoliosis and abnormal cerebral veins. |
A diffuse paradoxical cerebral air embolism of cortical
veins. |
|
|
B |
V |
A
47 year-old male with HIV infection and hemiplegia. |
Invasive aspergillosis of the CNS with secondary hemorrhagic
infarcts and subarachnoid hemorrhage in a patient with AIDS. |
|
|
B |
V |
A
54 year-old woman with a lesion compressing the medulla. |
Wegener's granulomatosis of the meninges. |
|
|
B |
V |
A
24 year-old male with headaches. |
Idiopathic disseminated giant cell arteritis (GCA). |
|
|
B |
V |
A 69
year-old man with left hemispheric necrotizing mass lesion. |
EBV-associated diffuse large B cell lymphoma and additional microglial
nodule encephalitis of the brainstem with associated severe hypoxic
injury of neurons. |
|
|
B |
V |
A 42 year-old man with a densely vascular spinal mass. |
De novo malignant ganglioglioma of the spinal cord with unusually
prominent dysplastic vessels (“malignant angio-ganglioma”). |
|
|
B |
V |
Newborn with intracranial mass. |
Chronic intracerebral hemorrhage of unknown etiology with
reactive changes of the surrounding brain tissue and focal
extramedullary erythropoiesis. |
|
|
B |
V |
A 19 year-old male with frontal lobe tumor. |
Cryptic arteriovenous malformation (AVM) with severe
hemosiderosis of left frontal lobe of brain. |
|
|
B |
V |
A 60 year-old diabetic male with transient ischemic attack. |
Cryptococcal meningitis with vasculitis and cerebral
infarct. |
|
|
B |
V |
A 28 weeks gestational age premature baby with lethargy and
coma. |
Thrombosis of internal cerebral veins. |
|
|
M |
F |
A 42
year-old man with Discoid lupus and progressive weakness. |
Hydroxychloroquine myopathy. |
|
|
M |
F |
A 54-year-old man with severe muscle weakness. |
Acute necrotizing myopathy (rhabdomyolysis) secondary to
lovastatin and niacin. |
|
|
M |
F |
A 32 year-old woman with anorexia nervosa. |
Myopathy with cytoplasmic bodies and multi-cores. These
findings are most consistent with a congenital myopathy or ipecac
(emetine) toxicity. |
|
|
M |
G |
A
67 year-old man with dyspnoea, weakness and raised creatine kinase. |
Amyloid myopathy and cardiac amyloidosis due to primary AL
amyloidosis. |
|
|
M |
G |
A
3 month-old boy with progressive weakness |
Lipid storage myopathy. |
|
|
M |
G |
A
31 year-old male with slowly progressive weakness. |
Hereditary myopathy with early respiratory failure (HMERF). |
|
|
M |
G |
A
2 month-old male with hypotonia and MTM1 gene mutation. |
X-linked myotubular myopathy. |
|
|
M |
G |
A
year-old man with proximal weakness and elevated creatine kinase. |
Becker muscular dystrophy (BMD). |
|
|
M |
G |
A 9
year-old female with progressive weakness. |
Manifesting
carrier of a dystrophinopathy with a duplication noted in exon 5-11 of
the dystrophin gene. Her X-inactivation studies showed marked skewing,
with 95% inactivation of the wild-type allele. |
|
|
M |
G |
A 48 year-old woman with chronic myalgias after exercise. |
McArdle’s disease (Glycogenosis type V, phosphorylase A
deficiency) |
|
|
M |
I |
A
45 year-old woman with progressive upper and lower extremity proximal
weakness. |
Anti-synthetase syndrome-associated myositis. |
|
|
M |
I |
A
62 year-old female with muscle pain and rash. |
Immune-mediated necrotizing myopathy, iNM or IMNM (Synonym:
necrotizing autoimmune myopathy, NAM) Most likely anti-synthetase
myopathy (ASM). |
|
|
M |
I |
A 63-year-old female with muscular atrophy. |
Macrophagic myofasciitis. |
|
|
M |
I |
A 56-year-old woman with left facial numbness. |
Nerve: Axonal degeneration with non-caseating granulomas and
vasculitis. Muscle: Granulomatous myositis. |
|
|
M |
NH |
A
77 year-old woman with polyneuropathy. |
Myopathy secondary to intravascular large B-cell lymphoma
(IVLBCL), non-germinal center subtype. |
|
|
N |
F |
A 70 year-old woman with SLE, paraproteinemia and
polyneuropathy. |
Toxic polyneuropathy induced by hydrochloroquine. |
|
|
N |
I |
A 71 year-old male with 4 decades of symptoms referable to
both central and peripheral nervous system. |
Chronic inflammatory demyelinating polyradiculoneuropathy
(CIDP) with onion bulb formation in hypertrophic nerves and co-existent
multiple sclerosis (MS). |
|
|
N |
I |
A 56-year-old woman with left facial numbness. |
Nerve: Axonal degeneration with non-caseating granulomas and
vasculitis. Muscle: Granulomatous myositis. |
|
|
N |
NH |
A
49 year-old man with headache, weight loss and cranial nerve
disturbances. |
Segment of nerve involved by adult T cell leukemia/lymphoma
(ATLL). |
|
|
N |
U |
A 71-year-old woman with progressive sensori-motor
polyneuropathy. |
Paraproteinemic (IgM) polyneuropathy with features of widely
spaced myelin, segmental demyelination, onion bulbs and axonal changes. |
|
|
N |
U |
A 51 year-old woman with new rapidly progressive weakness. |
Acute motor axonal neuropathy. |
|
|
N |
V |
A 66-year-old man with a subacute multi-system disorder and
polyneuropathy. |
Microvasculitis associated with systemic lupus erythematosus
(SLE). |
|
|
O |
NN |
A 41-year-old woman with a solitary lesion in the liver. |
Ectopic ependymoma of the liver. |
|
|
P |
F |
A 67 year-old man in coma requiring prolonged mechanical
ventilation. |
Massive adenohypophysial necrosis (few weeks old)
corresponding to "respirator pituitary". |
|
|
P |
I |
A
28 year-old woman with amenorrhoea and visual disturbance. |
Atypical pituitary adenoma with prominent lymphocytes
infiltration and germinal centers. |
|
|
P |
I |
An 82 year-old Caucasian male with progressive visual
deficits. |
Recurrent Pituitary Adenoma. Paranasal Sinus Contents with
Fungal Elements, consistent with Microascus species. |
|
|
P |
MO |
A
13 year-old girl with sellar mass. |
Germinoma. |
|
|
P |
NH |
A
63 year-old
man with dementia, ataxia and VI nerve palsy. |
Intravascular large B-cell lymphoma with extensive sellar
involvement. |
|
|
P |
NM |
A
50 year-old male with back pain and diplopia. |
Metastatic hepatocellular carcinoma. |
|
|
P |
NM |
A man in his mid-70’s with a sellar mass. |
Pituitary oncocytoma with metastatic malignant melanoma.
|
|
|
P |
NN |
A
79 year-old woman with headache and enlarging feet. |
Pituitary gangliocytoma associated
with acromegaly. |
|
|
P |
NN |
A
39 year-old woman with visual deterioration and a suprasellar mass. |
Sellar Melanocytoma. |
|
|
P |
NN |
A
57 year-old female with hemianopia and suprasellar mass. |
Granular cell tumor, neurohypophysis. |
|
|
P |
NN |
A
47 year-old woman with headache, eye pain and lesion involving the
cavernous sinus. |
Atypical teratoid rhabdoid tumor (AT/RT), sellar mass with
bone extension. |
|
|
P |
NN |
A
55 year-old man with electrolyte disturbance and fatigue. |
Spindle cell oncocytoma of adenohypophysis. |
|
|
P |
NN |
A 48 year
old with headache and hemianopia. |
Spindle cell oncocytoma of the adenohypophysis. |
|
|
P |
NN |
A
30 year-old woman with amenorrhoea and visual loss. |
Pituicytoma (WHO Grade I). |
|
|
P |
NN |
A
40 year-old woman with seizures and menstrual disorder. |
Pituicytoma. |
|
|
P |
NN |
59 year-old
male with pan-hypopituitarism. |
Pituicytoma. |
|
|
P |
NN |
A
61 year-old
man with hyponatremia. |
Schwannoma, intrasellar. |
|
|
P |
NN |
A 59 year-old woman with a sellar/suprasellar mass. |
Atypical granular cell tumor of the neurohypophysis. |
|
|
P |
NO |
Polyuria, polydipsia, headache and loss of consciousness. |
Papillary craniopharyngioma with dysplastic changes. |
|
|
P |
NO |
A
42 year-old male with AIDS presenting with confusion, headache and
lethargy. |
Germinoma, sellar area. |
|
|
P |
NO |
A
42 year-old male with thyroiditis and diabetes insipidus. |
Germinoma, sellar area. |
|
|
P |
NO |
A
54 year-old male with visual loss, facial pain and eye displacement. |
Growth Hormone-secreting Pituitary Carcinoma. |
|
|
P |
NO |
A
34 year-old man with intra and supra-sellar mass. |
Embryonal rhabdomyosarcoma arising from the pituitary. |
|
|
P |
NO |
A
33 year-old woman with headaches and visual loss. |
Paraganglioma, sellar region. |
|
|
P |
NO |
A
52 year-old male with Cushings and recurrent sellar mass. |
Pituitary adenoma, adenocorticotroph adenoma with Nelson’s
syndrome. |
|
|
P |
NO |
A
28 year-old woman with amenorrhoea and visual disturbance. |
Atypical pituitary adenoma with prominent lymphocytes
infiltration and germinal centers. |
|
|
P |
NO |
A 59
year-old female with suprasellar mass. |
Capillary
hemangioma. |
|
|
P |
NO |
A
35 year-old
woman with intrasellar and suprasellar lesion |
Concomitant
sparsely granulated growth hormone cell pituitary adenoma and
granulomatous giant cell hypophysitis with molecular pathological
detection of M. tuberculosis DNA. |
|
|
P |
NO |
A 59 year-old woman with an intrasellar lesion. |
Intrasellar glioneuronal hamartoma with GH-cell pituitary
adenoma and schwannoma-like component. |
|
|
P |
NO |
A 49-year-old woman with visual disturbances. |
Embryonal rhabdomysarcoma in the sella turcica. |
|
|
P |
NO |
A 20 year-old with a pituitary tumor. |
Germinoma. |
|
|
P |
U |
A 16 year-old female with headaches, lethargy and a
sellar/suprasellar mass. |
Rathke's Cleft Cyst. |
|
|
S |
C |
Developmental lesion overlying spine. |
Pacinian hyperplasia ("Pacinioma", pacinian neuroma)
associated with meningoradiculocele. |
|
|
S |
C |
A 2 year-old boy with lumbosacral mass. |
Lipomyelomeningocele with nephrogenic rests. |
|
|
S |
D |
A 25 year-old woman with progressive weakness during
pregnancy. |
Motor neuron disease with basophilic inclusions. |
|
|
S |
G |
A
79 year-old man with Parkinsonism, back pain, leg weakness and urinary
dysfunction. |
Gaucher disease Type I, bone of vertebral column. |
|
|
S |
G |
A 77 year-old man with dementia, motor dysfunction, and
liver disease. |
Acquired (Non-Wilsonian) hepatocerebral degeneration with
"shunt myelopathy". |
|
|
S |
I |
33 year old with lesion in
cervical cord. |
Necrotizing myelopathy possibly
related to the group defined as neuromyelitis optica spectrum disorders
(NMOSD). |
|
|
S |
I |
A
10-year-old girl with neck pain. |
Neuromyelitis optica. |
|
|
S |
MM |
A
62 year-old man with right sided weakness and incontinence. |
Metastatic small cell carcinoma of lung, spinal
intramedullary metastasis. |
|
|
S |
NH |
A
20 year-old lady with a paraspinal mass. |
Hodgkin's disease-mixed cellularity type. |
|
|
S |
NM |
A
69 year-old woman with leg weakness and spinal mass. |
Metastatic acinic cell carcinoma. Remote history of excised
parotid well-differentiated acinic cell carcinoma. |
|
|
S |
NN |
A
15 year-old boy with NF2 intracranial masses |
Mixed Tumor with Schwannoma and Meningioma Components. |
|
|
S |
NN |
A
55 year-old man with speech arrest. |
Drop metastasis of an anaplastic oligodendroglioma, spinal
cord. |
|
|
S |
NN |
A
32 year-old woman with paravertabral mass. |
Melanotic Schwannoma. |
|
|
S |
NN |
A
53 year-old female with lumbar mass. |
Malignant perineurioma (Malignant peripheral nerve sheath
tumor with perineural differentiation). |
|
|
S |
NN |
A
16 month-old male with head tilt, weakness, developmental delay and
spinal mass. |
Pilomyxoid Astrocytoma (WHO Grade II). |
|
|
S |
NN |
11 year-old boy with sacral pain and lesion in lower spinal
canal. |
Malignant peripheral nerve sheath tumor (MPNST) /
epithelioid and melanotic schwannoma. |
|
|
S |
NN |
A
48 year-old woman with progressive hemisensory loss. |
Extraventricular ganglioneurocytoma, WHO grade II (central
neurcytoma with ganglionic component), cervical spine. |
|
|
S |
NN |
A
46 year-old woman with leg numbness and spinal lesion. |
Glioneuronal tumor with neuropil-like islands (GTNI), spinal
cord. |
|
|
S |
NN |
A
25 year-old woman with lumbago and intradural masses. |
Myxopapillary ependymoma, WHO grade I, two foci in spinal
cord. |
|
|
S |
NN |
A
39 year-old man with syncope, nausea and vomiting.
|
Cerebellar oligodendroglioma with bone marrow metastasis. |
|
|
S |
NN |
A
46 year-old man with lower extremity tingling. |
Medulloblastoma, WHO Grade IV, consistent with late drop
metastasis. |
|
|
S |
NN |
A 55
year-old man with a paraspinal mass. |
Malignant
melanotic schwannoma. |
|
|
S |
NN |
A man in his mid-60s with intermittent paresthesia of the
abdomen and legs. |
Pilocytic astrocytoma, spinal cord. |
|
|
S |
NN |
A woman in her 50s with a cervical intra- and extraspinal
mass lesion. |
Malignant psammomatous melanotic schwannoma in a patient
without signs of carney complex, spinal cord. |
|
|
S |
NN |
A 47 year-old man with long-standing progressive
tetraparesis. |
Lymphoplasmacyte-rich meningioma, WHO grade I, multiple
en plaque.
|
|
|
S |
NN |
A 30 year-old male with various sensory abnormalities. |
Ganglioglioma, spinal cord. |
|
|
S |
NO |
A
63 year-old man with cauda equina syndrome. |
Spinal hibernoma (brown adipocytes
in an otherwise unremarkable bone marrow). |
|
|
S |
NO |
A
33 year-old man with paraparesis and lumbar mass. |
Epstein-Barr virus-associated smooth muscle tumor, spinal
cord. |
|
|
S |
NO |
A
11 year-old boy with lumbar intradural mass. |
Intradural, extramedullary granular cell tumor. |
|
|
S |
NO |
A 60 year
old man with lumbar mass. |
Spinal paraganglioma (WHO grade I). |
|
|
S |
NO |
A
64 year-old man with lumbar intradural mass. |
Capillary hemangioma, spinal cord. |
|
|
S |
NO |
A
24 year-old woman with acute back pain and spinal lesion. |
Ectopic adrenocortical adenoma of spinal canal, intradural,
extramedullary. |
|
|
S |
NO |
A 61
year-old woman with osteomalacia and a thoracic spine lesion. |
Phosphaturic Mesenchymal Tumor, Mixed Connective Tissue Variant
(PMT-MCT). |
|
|
S |
NO |
A 15-year-old female with progressive myelopathy. |
Ewing’s sarcoma (peripheral primitive neuroectodermal
tumor), vertebral column. |
|
|
S |
NO |
A 63 year-old woman with an intradural mass at the cauda
equina. |
Paraganglioma, gangliocytic variant. |
|
|
S |
NO |
A 13 year-old girl with back pain and leg weakness. |
Pigmented villonodular synovitis, vertebral column. |
|
|
S |
NO |
A 43 year-old Caucasian male with progressive right lower
extremity radicular pain. |
Paraganglioma, filum terminale. |
|
|
S |
U |
A
55 year-old Brazilian man with acute onset lower limb weakness and
Guillain-Barré syndrome. |
Leptomeningeal amelanotic melanomatosis and brain metastases
from gastric melanoma. |
|
|
S |
U |
A
55 year-old woman with leg pain. |
Intradural schwannoma in schwannomatosis. |
|
|
S |
U |
A
66 year-old
male with spinal mass at autopsy. |
Traumatic neuroma. |
|
|
S |
U |
A 35 year-old healthy man with enlarging right parotid mass. |
Castleman's disease, hyaline
vascular type, vertebral column. |
|
|
S |
U |
A 40 year-old Xhosa male with back pain and leg weakness. |
Extramedullary hematopoiesis, dural based spinal cord.
|
|
|
S |
U |
A 42 year-old male with back pain, progressive right leg
weakness and bilateral lower leg numbness. |
Giant cell tumor of hyperparathyroidism (Brown tumor),
thoracic spine. |
|
|
S |
V |
Female in late 60’s with progressive paraplegia and sensory
loss. |
Foix-Alajouanine syndrome (Spinal dural arteriovenous
fistula and related changes in spinal cord). |
|
|
S |
V |
A
67 year-old
male with progressive paraparesis. |
Subacute
necrotic myelitis/myelopathy (Foix-Alajouanine syndrome). |
|
|
S |
V |
A
56 year-old
male with left sided weakness. |
Cerebral
intraparenchymal myeloma. |
|
|
S |
V |
A year-old female with dural mass encircling cervical spinal
cord. |
Granulomatous dural infiltrate with vasculitis, giant cells,
and elevated c-ANCA titers; consistent with Wegener's granulomatosis
involving dura of cervical spinal cord. |
|
|
S |
V |
A year-old man with a history over 3 months of increasing
dyspnea and malaise. |
Spinal subarachnoid hemorrhage secondary to microscopic
polyangiitis (Idiopathic late-onset cerebellar ataxia). |