Thrombotic Microangiopathy (TMA)

Thrombotic Microangiopathy (TMA) is a comprehensive term that describes syndromes with similar pathologic and clinical features. We use the term, "primary TMA syndromes," to describe the disorders for which there is evidence supporting a defined abnormality as the probably cause. This section of our website focuses on 4 primary TMA syndromes:


George JN, Nester CM. Syndromes of thrombotic microangiopathy. New Eng J Med 2014; 310 (7): 654-666. [Full Text]


James N. George, M.D.

Professor of Medicine

Hematology-Oncology Section, Department of Medicine

Department of Biostatistics & Epidemiology, College of Public Health

University of Oklahoma Health Sciences Center



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