https://ouhsc.edu/platelets/Thrombocytopenia Parent Page: Thrombocytopenia id: 31762 Active Page: DITP Database from drug-dependent platelet-reactive antibody testing at the BloodCenter of Wisconsin, 1995-2014id:33495

DITP Database from drug-dependent platelet-reactive antibody testing at the BloodCenter of Wisconsin, 1995-2014

Results of the Testing for Drug-Dependent Platelet-Reactive Antibodies by the BloodCenter of Wisconsin

Data are from 1995-2015, provided with the permission of Daniel Bougie PhD, Janice McFarland MD, Brian Curtis, PhD and Richard Aster, MD

[+]: Indicates drugs for which drug-dependent platelet reactive antibodies [DDAb] were detected.
[-]: Indicates drugs for which samples were submitted for testing but no DDAb were detected
* Indicates drugs for which DDAb were identified in ten or more patients.
¹Indicates drugs for which DDAb were detected only with drug metabolites.
²Indicated drugs for which DDAb were detected for both intact, parent drug and metabolites.
Information about DDAb testing is available from the Platelet Neutrophil Immunology Laboratory here.

Drug DDAB

*ABCIXIMAB

+

*CARBAMAZEPINE

+

*CEFTRIAXONE

+

*EPTIFIBATIDE

+

*OXALIPLATIN

+

*PHENYTOIN

+

*PIPERACILLIN

+

*PIPERACILLIN/ TAZOBACTAM

+

*QUINIDINE

+

*QUININE

+

*RIFAMPIN

+

*SULFAMETHOXAZOLE/TRIMETHOPRIM

+

*TIROFIBAN

+

*VANCOMYCIN

+

 

ACETAMINOPHEN

+

ACETAMINOPHEN/HYDROCODONE

-

ACETAMINOPHEN/OXYCODONE

-

ACETAMINOPHEN/PROPOXYPHENE

-

ACYCLOVIR

-

ALBUTEROL

-

ALENDRONATE

-

ALLOPURINOL

-

ALPRAZOLAM

-

AMIODARONE

+

AMITRIPTYLINE

+

AMLODIPINE

-

AMLODIPINE/BENAZEPRIL

-

AMOXICILLIN

+

AMOXICILLIN/CLAVULANATE

-

AMPHOTERICIN B

-

AMPICILLIN

+

ARGATROBAN

+

ASPIRIN

+

ATENOLOL

+

ATORVASTATIN

-

ATOVAQUONE

-

AZACITIDINE

+

AZITHROMYCIN

-

AZTREONAM

-

BENAZEPRIL

-

BENZTROPINE

-

BIVALIRUDIN

-

BUDESONIDE

-

BUMETANIDE

+

BUPROPION

+

BUSPIRONE

-

CAPTOPRIL

-

CARBIDOPA

-

CARVEDILOL

-

CASPOFUNGIN

-

CEFADROXIL

+

CEFAZOLIN

+

CEFEPIME

+

CEFPODOXIME

+

CEFTAZIDIME

+

CEFTIZOXIME

+

CEFTRIAXONE

+

CEFUROXIME

-

CELECOXIB

+

CEPHALEXIN

+

CHLORPROMAZINE

-

CILASTATIN

-

CILASTATIN/IMIPENEM

-

CIMETIDINE

-

CIPROFLOXACIN

+

CITALOPRAM

-

CLARITHROMYCIN

-

CLAVULANATE POTASSIUM

-

CLINDAMYCIN

+

CLONAZEPAM

-

CLONIDINE

-

CLOPIDOGREL

-

COLCHICINE

-

CYCLOSPORINE

+

DAPSONE

-

DIAZEPAM

-

DICLOFENAC

-

DIGOXIN

-

DILTIAZEM

-

DIPHENHYDRAMINE

+

DOBUTAMINE

+

DOCUSATE

-

DONEPEZIL

-

DOPAMINE

-

DOXAZOSIN

-

DOXYCYCLINE

+

ENALAPRIL

-

ENOXAPARIN

-

EPOETIN ALFA

-

ESCITALOPRAM

-

ESOMEPRAZOLE

+

ETHAMBUTOL

+

ETHINYLESTRADIOL/NORGESTIMATE

-

EZETIMIBE

-

FAMOTIDINE

-

FELODIPINE

+

FENOFIBRATE

-

FENTANYL

+

FEXOFENADINE

+

FINASTERIDE

-

FLUCONAZOLE

-

FLUOROURACIL

-

FLUOXETINE

-

FLUVASTATIN

-

FOSINOPRIL

-

FUROSEMIDE

+

GABAPENTIN

-

GENTAMICIN

-

GLIMEPIRIDE

-

GLIPIZIDE

-

GLYBURIDE

-

HALOPERIDOL

+

HYDRALAZINE

-

HYDROCHLOROTHIAZIDE

-

HYDROCHLOROTHIAZIDE/LOSARTAN

-

HYDROCORTISONE

-

HYDROMORPHONE

-

HYDROXYCHLOROQUINE

+

IBRUTINIB

+

IBUPROFEN

+

IMIPENEM (see CILASTATIN/IMIPENEM)

INFLIXIMAB

-

INSULIN

-

IPRATROPIUM

-

IRBESARTAN

-

IRINOTECAN

+

ISONIAZID

-

ISOSORBIDE

-

ISOTRETINOIN

-

LABETALOL

-

LAMOTRIGINE

+

LANSOPRAZOLE

+

LEPIRUDIN

-

LEUCOVORIN

+

LEVETIRACETAM

-

LEVOFLOXACIN

+

LEVOTHYROXINE

-

LIDOCAINE

-

LINEZOLID

-

LISINOPRIL

+

LOPERAMIDE

-

LORACARBEF

+

LORATADINE

-

LORAZEPAM

+

LOSARTAN

+

LOVASTATIN

-

LOVASTATIN/NIACIN

-

MEFLOQUINE

-

MELOXICAM

-

MEROPENEM

-

METFORMIN

-

METHOTREXATE

-

METHYLDOPA

-

METHYLPHENIDATE

-

METHYLPREDNISOLONE

+

METOCLOPRAMIDE

-

METOLAZONE

-

METOPROLOL

-

METRONIDAZOLE

+

MIDAZOLAM

-

MILRINONE

-

MINOCYCLINE

-

MINOXIDIL

-

MIRTAZAPINE

-

MONTELUKAST

-

MORPHINE

-

MOXIFLOXACIN

-

MYCOPHENOLATE

-

NAFCILLIN

+

NAPROXEN

+

NEFAZODONE

-

NIFEDIPINE

-

NITROFURANTOIN

+

NITROGLYCERIN

-

NIZATIDINE

+

NOREPINEPHRINE

-

NYSTATIN

-

OLANZAPINE

+

OLMESARTAN

+

OMEPRAZOLE

-

ONDANSETRON

+

OXACILLIN

-

OXAPROZIN

+

OXCARBAZEPINE

+

OXYCODONE

-

PANTOPRAZOLE

+

PAPAVERINE

+

PAROXETINE

+

PENICILLIN

-

PHENOBARBITAL

+

PIOGLITAZONE

-

PRAVASTATIN

-

PREDNISONE

-

PREGABALIN

-

PROCAINAMIDE

+

PROPOXYPHENE

+

PROPRANOLOL

+

PROPYLTHIOURACIL

+

PROTAMINE

+

QUETIAPINE

+

QUINAPRIL

-

RABEPRAZOLE

-

RALOXIFENE

-

RAMIPRIL

-

RANITIDINE

+

RIFABUTIN

-

RIFAXIM
+

RISEDRONIC ACID

-

RISPERIDONE

-

RITUXIMAB

+

ROSUVASTATIN

-

SERTRALINE

+

SILDENAFIL

-

SIMVASTATIN

+

SOTALOL

-

SPIRONOLACTONE

+

SUCRALFATE

-

SULFISOXAZOLE

+

SURAMIN

+

TACROLIMUS

-

TAMOXIFEN

-

TAMSULOSIN

-

TERAZOSIN

-

TETRACYCLINE

-

TOBRAMYCIN

-

TOLTERODINE

-

TOPIRAMATE

-

TRAMADOL

-

TRAZODONE

+

TRIAMTERENE

-

TRIAZOLAM

-

URSODIOL

-

VALACYCLOVIR

-

VALGANCICLOVIR

-

VALPROIC ACID

+

VALSARTAN

-

VENLAFAXINE

-

VERAPAMIL

+

VORICONAZOLE

+

WALNUTS (ENGLISH)
+

WARFARIN

-

ZOLMITRIPTAN

+

ZOLPIDEM

-

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